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TerminatedPhase 2ACTRN12611000931976

Telmisartan in the management of abdominal aortic aneurysm

The effects of Telmisartan, an angiotensinII type 1 receptor blocker, in reducing AAA growth in patients with abdominal aortic aneurysm.

Sponsor

James Cook University

Enrollment

300 participants

Start Date

Sep 9, 2011

Study Type

Interventional

Conditions

Abdominal Aortic Aneurysm

Summary

The primary purpose of the study is to investigate telmisartan as a novel therapy for patients with abdominal aortic aneurysms. We hypothesize that telmisartan will reduce AAA growth.

Eligibility

Sex: Both males and femalesMin Age: 40 YearssMax Age: 85 Yearss

Plain Language Summary

Simplified for easier understanding

This trial investigates whether the blood pressure medication telmisartan can slow the growth of small abdominal aortic aneurysms (35-49mm). Adults aged 40-85 with a stable small aneurysm that does not yet require surgical repair are eligible. The study aims to find a medication-based approach to managing aneurysms and potentially delaying or preventing the need for surgery.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Angiotensin II type 1 receptor blocker, oral tablet, 40mg daily for 24 months.

Angiotensin II type 1 receptor blocker, oral tablet, 40mg daily for 24 months.

Locations(7)

Mackay Base Hospital - Mackay

NSW,QLD,SA,WA,VIC, Australia

The Townsville Hospital - Douglas

NSW,QLD,SA,WA,VIC, Australia

Royal Brisbane & Womens Hospital - Herston

NSW,QLD,SA,WA,VIC, Australia

The Queen Elizabeth Hospital - Woodville

NSW,QLD,SA,WA,VIC, Australia

Mater Hospital Pimlico - Pimlico

NSW,QLD,SA,WA,VIC, Australia

California, United States of America

Leiden, Netherlands

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ACTRN12611000931976

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