Role of oral ketamine and dexmedetomidine in adults burns dressing. A double blind randomised cross over study.
Role of oral ketamine and dexmedetomidine in adults burns dressing for evaluating safety and efficacy:A double blind randomised cross over study
Jawaharlal Nehru institute of Medical education and research
45 participants
Aug 1, 2010
Interventional
Conditions
Summary
To evaluate the analgesic effect and safety of dexmedetomidine and ketamine in adults during burns dressing changes
Eligibility
Inclusion Criteria1
- adult patients with burns 20 to 50 % body surface area
Exclusion Criteria1
- facial burns preventing oral intake
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Interventions
Patients will be given morphine intra muscular( IM) 0.1 mg/kg;; local anesthetic soaked gauzes will be applied on the wounds oral ketamine 5 mg/kg will be given ;visual analogue scale( VAS) score; sedation score; vital parameters will be recorded; the next day patient cross over to dexmedetomidine group; they will receive morphine similar to the previous day and dexmedetomidine 4ug/kg all the above parameters recorded
Locations(1)
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ACTRN12612000700831