Comparison of Contrast Enhanced UltraSound to Magnetic Resonance Imaging for the detection of synovitis in patients with haemophilic arthropathy. A pilot study

People with haemophilia — a bleeding disorder — can develop joint damage called haemophilic arthropathy, where joint bleeding causes chronic swelling and inflammation in the joint lining (synovitis). This pilot study is testing whether contrast-enhanced ultrasound (CEUS) — an ultrasound technique using a contrast agent injected into the bloodstream — is as good as MRI (the current standard test) for detecting synovitis. If so, CEUS could offer a faster, less claustrophobic alternative to MRI. You may be eligible if: - You are between 18 and 70 years old - You have been diagnosed with haemophilic arthropathy - Physical examination alone cannot clearly confirm whether you have synovitis (joint inflammation) You may NOT be eligible if: - You are pregnant or breastfeeding - You have a right-to-left cardiovascular shunt or pulmonary hypertension - You have kidney impairment - You have unstable heart disease - You have a known allergy to ultrasound contrast agents Talk to your doctor about whether this trial might be right for you.