Comparison of Contrast Enhanced UltraSound to Magnetic Resonance Imaging for the detection of synovitis in patients with haemophilic arthropathy. A pilot study
Dr Anne Powell
40 participants
Sep 23, 2013
Interventional
Conditions
Summary
The aim of this project is to demonstrate that contrast enhanced ultrasound is an equally effective method for detecting synovitis in patients with haemophilia in whom the diagnosis of synovitis (joint capsule inflammation) from physical examination is unclear. Currently, MRI is the screening tool for synovitis in this population; however it is time consuming, claustrophobic for some patients and has long waiting times. Contrast-enhanced ultrasound is the application of ultrasound contrast medium to traditional medical sonography. Ultrasound contrast agents may be used during an ultrasound examination to improve the clarity and accuracy of a conventional ultrasound image.
Eligibility
Inclusion Criteria1
- Adult patients with haemophiliac arthropathy
Exclusion Criteria1
- Pregnancy or breast feeding, right to left cardiovascular shunts, pulmonary hypertension, renal impairment, unstable cardiac disease, hypersensitivity to contrast agents
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Interventions
Contrast enhanced ultrasound, a non ionising diagnostic imaging study using intravenously administered microbubble contrast ("Definity"). This study is performed on each participant on a single occasion for the affected joint, and takes approximately 30-45 minutes.
Locations(1)
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ACTRN12614000662662