Detection of Individuals with Preclinical, Prodromal and Mild Alzheimer's Disease for Therapeutic Trials.

This study is looking for people who may have very early or mild Alzheimer's disease. Researchers want to use a special brain scan called an amyloid PET scan to help find people who might benefit from future treatments. This scan can detect a protein buildup in the brain that is linked to Alzheimer's disease before serious memory problems develop. You may be eligible if: - You are between 50 and 85 years old - You have mild memory or thinking problems (mild cognitive impairment) or mild Alzheimer's disease - You have completed at least 6 years of school - You can speak and understand English well enough for memory testing - You can hear and see well enough for the tests - You are able to have an MRI scan - Your MMSE (memory test) score is 20 or above - You are interested in taking part in research You may NOT be eligible if: - You have another brain or nervous system disease besides Alzheimer's - You have a serious mental illness - You have been diagnosed with cancer in the last 5 years (not counting skin cancer or early-stage prostate cancer) - You have a problem with drug or alcohol use - You cannot have an MRI scan (for example, due to a metal implant) Talk to your doctor about whether this trial might be right for you.