Probiotics use impact on metabolic markers, body composition, gut microbiota and immunity markers in prediabetic adolescents.

This study is looking at whether probiotics (beneficial live bacteria) can help prevent or slow the development of type 2 diabetes in teenagers and young adults who currently have pre-diabetes. Researchers will measure blood sugar control, body composition, gut bacteria, and immune markers. You may be eligible if: - You are between 12 and 20 years old - You have been diagnosed with pre-diabetes (elevated but not yet diabetic blood sugar levels) You may NOT be eligible if: - You have short-bowel syndrome with lactic acid build-up - You are currently hospitalised - You have an active infection of any kind - You have an immune system deficiency - You have a hormonal condition that causes diabetes (e.g., Cushing's syndrome) - You have taken antibiotics in the past month or consumed probiotic products regularly - You have epilepsy or atopic dermatitis (eczema) - You are pregnant or may be pregnant - You have metal prostheses or implanted devices such as a pacemaker - You have a serious chronic illness such as cancer Talk to your doctor about whether this trial might be right for you.