Prediabetes Clinical Trials

39 recruiting

Frequently Asked Questions

Common questions about Prediabetes clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 46 trials

Recruiting
Not Applicable

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

Metabolic SyndromeDiabetes Mellitus, Type 2Prediabetes
Cleerly, Inc.7,500 enrolled115 locationsNCT06112418
Recruiting
Not Applicable

A Clinical Trial to Examine the Efficacy and Safety of an Investigational Product With and Without Use of Semaglutide on Glycemic Response in Adults With Prediabetes or Type 2 Diabetes

Prediabetes / Type 2 Diabetes
QuickSilver Scientific90 enrolled1 locationNCT07195994
Recruiting
Not Applicable

Behavioral Approach for Latinas Addressing Nutrition, Cravings, and Eating Patterns to Prevent Type 2 Diabetes

PrediabetesObesity (Body Mass Index >30 kg/m2)
University of California, San Diego30 enrolled1 locationNCT07478263
Recruiting
Not Applicable

Whole Food for Families: A Pilot RCT of a Dietary Guidelines-Based Intervention to Prevent Type 2 Diabetes

Diet, HealthyPrediabetesNutritional and Metabolic Diseases
Vanderbilt University30 enrolled1 locationNCT06482944
Recruiting
Not Applicable

Nested Pilot Study Comparing Two Treatments to Reduce Type 2 Diabetes Risk in At-Risk Delawareans

Prediabetes
University of Delaware40 enrolled1 locationNCT07450118
Recruiting
Not Applicable

Human Immunodeficiency Virus (HIV) Food Insecurities

Type 2 Diabetes Mellitus (T2DM)PrediabetesHIV+2 more
Wake Forest University Health Sciences200 enrolled1 locationNCT04943861
Recruiting
Not Applicable

Remotely Delivered Resistance Training for Cardiometabolic Health Among Black Women

Resistance TrainingOverweight or ObesityPrehypertension (Elevated Blood Pressure) or Hypertension+1 more
University of Alabama at Birmingham36 enrolled1 locationNCT06360536
Recruiting

Blood Markers of Early Pancreas Cancer

Genetic Predisposition to DiseaseDiabetes Mellitus, Type 2Chronic Pancreatitis+3 more
University of Nebraska1,250 enrolled1 locationNCT03568630
Recruiting
Not Applicable

Mobile Health Dietary Intervention for Stroke Survivors With Prediabetes or Type 2 Diabetes

PrediabetesType 2 DiabetesStroke Recurrence
University of Hawaii40 enrolled1 locationNCT07120334
Recruiting
Not Applicable

Metabolic and Inflammatory Outcomes of the Ketogenic Diet Comparing Saturated and Unsaturated Fat Sources

Diabetes Mellitus, Type 2PrediabetesOverweight and Obesity
University of Alberta175 enrolled1 locationNCT05681468
Recruiting

Medically Intensive Nutrition Therapy Program for Obesity and Diabetes in a Low-income Population

ObesityOverweightPrediabetes+1 more
Massachusetts General Hospital20 enrolled1 locationNCT05799222
Recruiting
Not Applicable

Food as Medicine for HIV and Diabetes

Diabetes Mellitus, Type 2HIV InfectionsPrediabetes
University of North Carolina, Chapel Hill200 enrolled1 locationNCT05026723
Recruiting
Not Applicable

Post Prandial Individual Responses to Different Foods

HealthyDiabetes Mellitus, Type 2Prediabetes
Stanford University100 enrolled1 locationNCT06989164
Recruiting
Not Applicable

How a Mediterranean Diet With Potatoes Impacts Heart and Metabolic Health in Adults With Pre-Diabetes

HypertensionPrediabetesGlycemic Control+7 more
University of Nevada, Las Vegas60 enrolled2 locationsNCT06817252
Recruiting
Not Applicable

New T-UP: Engaging Vulnerable Students in Diabetes Prevention

PrediabetesType 2 Diabetes
University of California, Los Angeles80 enrolled1 locationNCT07225218
Recruiting
Not Applicable

Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention

ObesityCardiometabolic SyndromeDiet, Healthy+9 more
Ohio State University340 enrolled1 locationNCT06055036
Recruiting
Not Applicable

Insulin and Insulin Pulses During Fasting

Prediabetes
Mayo Clinic60 enrolled1 locationNCT06424015
Recruiting
Not Applicable

WeArable teChnology daTa driVen digitAl healTh cOachINg (ACTIVATION)- A Mixed-methods Study

HypertensionType 2 Diabetes Mellitus (T2DM)Prediabetes+3 more
Alexandra Hospital1,700 enrolled1 locationNCT06752772
Recruiting
Not Applicable

Effects of Walking in Greenspace and the Built Environment in Adults With Prediabetes: A Randomized Crossover Trial

PrediabetesStress and AnxietyHeart Rate Variability (HRV)+1 more
University of Minnesota216 enrolled3 locationsNCT06365723
Recruiting
Not Applicable

Precise Eating Time to Improve Glycemic Control and Cardiometabolic Health in Prediabetes and Diabetes

PrediabetesType 2 DiabetesObesity &Amp; Overweight
German Institute of Human Nutrition30 enrolled1 locationNCT07171281