Prediabetes Clinical Trials

52 recruiting

Prediabetes Trials at a Glance

49 actively recruiting trials for prediabetes are listed on ClinicalTrialsFinder across 6 cities in 15 countries. The largest study group is Not Applicable with 34 trials, with the heaviest enrollment activity in London, Los Angeles, and Birmingham. Lead sponsors running prediabetes studies include Georgia State University, German Institute of Human Nutrition, and University of Alabama at Birmingham.

Browse prediabetes trials by phase

Treatments under study

About Prediabetes Clinical Trials

Looking for clinical trials for Prediabetes? There are currently 52 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Prediabetes trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Prediabetes clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 49 trials

Recruiting

Pharmacist-Led Continuous Glucose Monitoring for Prediabetes

Prediabetes
University of South Florida40 enrolled2 locationsNCT07529366
Recruiting
Not Applicable

Whey Protein Ingestion and Glucose Control in Pre- and Post Diabetic Individuals

Prediabetes / Type 2 Diabetes
University of Arkansas40 enrolled1 locationNCT06694155
Recruiting
Phase 2

Efficacy and Safety of Oral Controlled-release Nicotinic Acid (CIR-NA) for the Remission of Prediabetes. (CONCEPT)

Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
University Hospital Schleswig-Holstein390 enrolled2 locationsNCT07286747
Recruiting
Phase 2

MOTS-c for Improving Insulin Sensitivity in Adults With Prediabetes and Overweight/Obesity

Insulin ResistancePrediabetesOverweight/Obesity
Hudson Biotech120 enrolled1 locationNCT07505745
Recruiting
Not Applicable

Continuous Glucose Monitoring (CGM) in Prediabetes With Community Based Recruitment

Prediabetes
David S Black, PhD50 enrolled1 locationNCT07477249
Recruiting
Not Applicable

Probiotic Impact on Cognitive Performance, and Metabolic Outcomes in Overweight Young Adults With Impaired Glucose Regulation

Cognitive DysfunctionPrediabetes (Insulin Resistance, Impaired Glucose Tolerance)Overweight (BMI > 25)+3 more
Leeds Beckett University70 enrolled1 locationNCT07073781
Recruiting
Not Applicable

Fiber mHealth Intervention for Prediabetes

Prediabetes
University of Oklahoma80 enrolled1 locationNCT07491653
Recruiting
Not Applicable

Peanuts for Cardiometabolic, Brain, and Intestinal Health

AdultPrediabetesCognition+5 more
Georgia State University72 enrolled1 locationNCT06867198
Recruiting
Not Applicable

Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes

Arterial StiffnessBody CompositionAdult+9 more
Georgia State University30 enrolled1 locationNCT06735651
Recruiting
Not Applicable

Behavioral Approach for Latinas Addressing Nutrition, Cravings, and Eating Patterns to Prevent Type 2 Diabetes

PrediabetesObesity (Body Mass Index >30 kg/m2)
University of California, San Diego30 enrolled1 locationNCT07478263
Recruiting
Not Applicable

Effect of Chronic Exposure to Nextida GC-B on Glycemic Control in Adults With Normoglycemia or Prediabetes

PrediabetesGlycemic ControlNormoglycemia
Rousselot BVBA60 enrolled1 locationNCT07149064
Recruiting
Not Applicable

A Clinical Trial to Examine the Efficacy and Safety of an Investigational Product With and Without Use of Semaglutide on Glycemic Response in Adults With Prediabetes or Type 2 Diabetes

Prediabetes / Type 2 Diabetes
QuickSilver Scientific90 enrolled1 locationNCT07195994
Recruiting
Not Applicable

Profile and Regulatory Network of Exercise in Improving Metabolic Phenotypes of Patients With Prediabetes

Prediabetes
Shanghai Zhongshan Hospital40 enrolled1 locationNCT06633575
Recruiting
Not Applicable

Nested Pilot Study Comparing Two Treatments to Reduce Type 2 Diabetes Risk in At-Risk Delawareans

Prediabetes
University of Delaware40 enrolled1 locationNCT07450118
Recruiting
Not Applicable

WatchWell: Simple and Practical Strategies to Reduce the Negative Health Impact of Sedentary Screen Time

ObesityCardiovascular DiseasesPrediabetes+1 more
Arizona State University30 enrolled1 locationNCT06963736
Recruiting
Not Applicable

Pilot Study of "Bottarga" Supplementation: A Little-known, Sustainable "Blue" Food

DiabetesPrediabetesHigh Cholesterol/Hyperlipidemia
Cambridge Health Alliance20 enrolled1 locationNCT06988462
Recruiting
Not Applicable

Effect of a Nutritional Product Containing Carob Extract on Carbohydrate Metabolism in Glucose-intolerant Subjects

Prediabetes
Universidad Católica San Antonio de Murcia30 enrolled1 locationNCT07420998
Recruiting
Early Phase 1

Crocus Sativus Tepals Water Extract in Obesity and Prediabetes

Prediabetes
University of Primorska20 enrolled1 locationNCT07261475
Recruiting
Not Applicable

Remotely Delivered Resistance Training for Cardiometabolic Health Among Black Women

Resistance TrainingOverweight or ObesityPrehypertension (Elevated Blood Pressure) or Hypertension+1 more
University of Alabama at Birmingham36 enrolled1 locationNCT06360536
Recruiting
Not Applicable

Development of an Inclusive Adaptive Treatment Strategy for Weight Loss in People With Prediabetes Using a Sequential Multiple Assignment Randomized Trial

Obesity and OverweightPrediabetesDisabilities
University of Alabama at Birmingham30 enrolled1 locationNCT06976307