Australian Centre of Excellence in Melanoma Imaging & Diagnosis Cohort Study

Participants will undergo three-dimensional total body (excluding skin beneath underwear and scalp) photography using the VECTRA whole-body scanner (VECTRA WB360 Serial Number WB00009, Canfield Scientific Inc, Parsippany, NJ, USA). The VECTRA whole-body scanner consists of 92 cameras with white or cross-polarised lighting, which simultaneously captures images to construct a digital 3D avatar of the participant, providing a record of all pigmented and non-pigmented skin lesions including naevi. A melanographer and dermatologically-trained medical practitioner will conduct the study visits and conduct the 3D total body photography. Participants will also complete questionnaires to obtain information on their demographics, sun behaviour, quality of life, skin cancer history and medical history. Study clinic visits will take approximately 30 minutes to an hour. The frequency of follow-up clinic visits will be based on the participant’s melanoma risk for the study duration of 3 years. The participant's risk will be assessed using a validated melanoma risk assessment tool developed by the NSW team. Participants' melanoma risk will be assessed at each visit; thus, if their melanoma risk changes, the participant will be reassigned into the corresponding melanoma risk level group. 1. Low/Average Risk Group Participants with a low or average risk of melanoma will be seen at the clinic for repeat 3D total body photography and dermoscopy every 24 months. In some cases, participants may be asked to return in 12 months’ time to monitor any changes suspicious skin lesions, on the discretion of the dermatologist. 2. High Risk Group Participants identified as having high risk of melanoma will undergo 3D total body photography and dermoscopy at the clinic every 12 months. In some instances, the dermatologist may wish to see some participants return in 6 months’ time to monitor any changes in suspicious skin lesions. 3. Very High Risk Group Participants identified as having very high risk of melanoma will undergo 3D total body photography and dermoscopy at the clinic every 6 months for the duration of the study. In some instances, the dermatologist may wish to see some participants return in 3 months’ time to monitor any changes in suspicious skin lesions. All participants will complete 12-monthly follow-up questionnaires about their sun behaviour, skin checks and quality of life.