The Healthy Optimal Australian Microbiome (HOAM) Study

Exclusion Criteria147

• Adolescent active
• Participant is not aged between 13-18 years old
• Participant does not regularly exercise outside of school
• Accessibility and consent exclusions
• Participant is not able to provide own consent or have consent provided for them legally
• Participant requires interpretive language services to communicate in English
• Participant is not willing and able to provide a stool, blood and oral sample for this study.
• Participant is not willing and able to complete the questionnaire-based and physical assessments in this study.
• Participant consumes more than one standard alcoholic beverage per day on average and/or consumes more than 4 standard drinks on one occasion.
• Participant smokes or uses vapour-producing devices containing tobacco or other combustible or vaporisable products (including Cannabis in any form) intended for direct inhalation into the lungs.
• Participant has made a major change to diet in the past month prior to enrolment
• Participant suffers from acute or chronic medical ailment
• Participant has a history of disease, cancer, or congenital abnormality
• Participant has developmental delay, or behavioural condition (e.g. attention deficit disorder, attention deficit/hyperactivity disorder, autism spectrum disorder, Asperger syndrome)
• Participant resides in same home (and uses the same toilet) as someone who uses chemotherapy, immunosuppressive, antineoplastic or cytotoxic agents
• Participant has had previous surgeries (excluding for treatment of bone fractures, or accidental injury)
• Participant has previously suffered from/currently suffers from a mental condition including anxiety or depression
• Participant regularly takes medication for a chronic medical issue including topical, inhaled, oral, injectable medications
• Participant regularly suffers from chronic or acute pain
• Participant suffers from chronic or acute stress
• Participant suffers from insomnia
• Participant has chronic illness such as asthma
• Participant has diagnosed food allergy or intolerance
• Participant has experienced recent cause of grief or trauma, or is experiencing ongoing mental distress (i.e. School bullying, domestic violence)
• Adolescent inactive
• Participant is not aged between 13-18 years old
• Participant is not overweight or obese (BMI <85th percentile for age and sex)
• Participant engages in regular physical activity outside of school in addition to school-based activities.
• Participant is not able to provide own consent or have consent provided for them legally
• Participant requires interpretive language services to communicate in English
• Participant is not willing and able to provide a stool, blood, urine and oral sample for this study.
• Participant is not willing and able to complete the questionnaire-based and physical assessments in this study.
• Participant consumes more than one standard alcoholic beverage per day on average and/or consumes more than 4 standard drinks on one occasion.
• Participant smokes or uses vapour-producing devices containing tobacco or other combustible or vaporisable products (including Cannabis in any form) intended for direct inhalation into the lungs.
• Participant has made a major change to diet in the past month prior to enrolment
• Young adult active
• Participant is not aged between 19-45 years old.
• Participant does not regularly exercise greater than 3 hours per week.
• [Subgroup, Professional and semi-professional athletes
• Participant does not undertake sport at a professional or semi-professional level]
• Participant is not able to provide own consent
• Participant requires interpretive language services to communicate in English
• Participant is not willing and able to provide a stool, blood and oral sample for this study.
• Participant is not willing and able to complete the questionnaire-based and physical assessments in this study.
• Participant consumes more than one standard alcoholic beverage per day on average and/or consumes more than 4 standard drinks on one occasion.
• Participant smokes or uses vapour-producing devices containing tobacco or other combustible or vaporisable products (including Cannabis in any form) intended for direct inhalation into the lungs.
• Participant has made a major change to diet in the past month prior to enrolment
• Participant has taken any antibiotic medication within the past 3 months.
• Participant is undergoing ongoing medical intervention or tests.
• Participant suffers from acute or chronic illness of any description.
• Participant has a history of disease, cancer, or congenital abnormality.
• Participant is dependent on medication for an acute or chronic illness, ongoing medical condition or complaint.
• Participant regularly suffers from chronic or acute pain.
• Participant has diagnosed food allergy or intolerance.
• Participant has experienced recent cause of grief or trauma.
• Participant is pregnant or is within 1-year post-pregnancy.
• Participant is lactating, and/or currently breastfeeding.
• Participant has undergone any major surgery within lifetime (excludes orthopaedic and dental surgery).
• Participant suffers from chronic, or acute skin condition (ie. Dermatitis, eczema, psoriasis).
• Participant has undergone major GI surgery such as bowel resection other previous bariatric procedure
• Young adult inactive
• Participant is not aged between 19-45 years old.
• Participant engages in regular physical activity >3 hours per week.
• Participant is not able to provide own consent
• Participant requires interpretive language services to communicate in English
• Participant is not willing and able to provide a stool, blood, urine and oral sample for this study.
• Participant is not willing and able to complete the questionnaire-based and physical assessments in this study.
• Participant consumes more than one standard alcoholic beverage per day on average and/or consumes more than 4 standard drinks on one occasion.
• Participant smokes or uses vapour-producing devices containing tobacco or other combustible or vaporisable products (including Cannabis in any form) intended for direct inhalation into the lungs.
• Participant has made a major change to diet in the past month prior to enrolment
• Participant has taken any antibiotic medication within the past 3 months.
• Participant has undergone major GI surgery such as bowel resection other previous bariatric procedure
• [for athlete group, participant does not train for an activity where they compete at a professional or competitive level or engage in high level activity as part of their work]
• Adult active
• Group specific exclusions
• Participant is not aged between 46-65 years old.
• Participant does not regularly exercise greater than 3 hours per week.
• Participant is not able to provide own consent
• Participant requires interpretive language services to communicate in English
• Participant is not willing and able to provide a stool, urine, blood and oral sample for this study.
• Participant is not willing and able to complete the questionnaire-based and physical assessments in this study.
• Participant consumes more than one standard alcoholic beverage per day on average and/or consumes more than 4 standard drinks on one occasion.
• Participant smokes or uses vapour-producing devices containing tobacco or other combustible or vaporisable products (including Cannabis in any form) intended for direct inhalation into the lungs.
• Participant has made a major change to diet in the past month prior to enrolment
• Participant has taken any antibiotic medication within the past 3 months.
• Participant is undergoing ongoing medical intervention or tests.
• Participant suffers from acute or chronic illness of any description.
• Participant has a history of disease, cancer, or congenital abnormality.
• Participant is dependent on medication for an acute or chronic illness, ongoing medical condition or complaint.
• Participant regularly suffers from chronic or acute pain.
• Participant has diagnosed food allergy or intolerance.
• Participant has experienced recent cause of grief or trauma.
• Participant is pregnant or is within 1-year post-pregnancy.
• Participant is lactating, and/or currently breastfeeding.
• Participant has undergone any major surgery within lifetime (excludes orthopaedic and dental surgery).
• Participant suffers from chronic, or acute skin condition (ie. Dermatitis, eczema, psoriasis).
• Participant has undergone major GI surgery such as bowel resection other previous bariatric procedure
• Athlete
• As for young adult group plus
• Participant must be actively training for and competing at a competitive or professional level or be highly active as part of their profession.
• Adult Inactive
• Participant is not aged between 46-65 years old.
• Participant does not regularly exercise greater than 3 hours per week.
• Participant is not able to provide own consent
• Participant requires interpretive language services to communicate in English
• Participant is not willing and able to provide a stool, blood, urine and oral sample for this study.
• Participant is not willing and able to complete the questionnaire-based and physical assessments in this study.
• Participant consumes more than one standard alcoholic beverage per day on average and/or consumes more than 4 standard drinks on one occasion.
• Participant smokes or uses vapour-producing devices containing tobacco or other combustible or vaporisable products (including Cannabis in any form) intended for direct inhalation into the lungs.
• Participant has made a major change to diet in the past month prior to enrolment
• Participant has taken any antibiotic medication within the past 3 months.
• Participant is undergoing ongoing medical intervention or tests.
• Participant suffers from acute or chronic illness of any description.
• Participant has a history of disease, cancer, or congenital abnormality.
• Participant is dependent on medication for an acute or chronic illness, ongoing medical condition or complaint.
• Participant regularly suffers from chronic or acute pain.
• Participant has diagnosed food allergy or intolerance.
• Participant has experienced recent cause of grief or trauma.
• Participant is pregnant or is within 1-year post-pregnancy.
• Participant is lactating, and/or currently breastfeeding.
• Participant has undergone any major surgery within lifetime (excludes orthopaedic and dental surgery).
• Participant suffers from chronic, or acute skin condition (ie. Dermatitis, eczema, psoriasis).
• Participant has undergone major GI surgery such as bowel resection other previous bariatric procedure
• Senior adults
• Participant is not aged 66-94
• Participant is not able to provide own consent or have consent provided for them legally
• Participant requires interpretive language services to communicate in English
• Participant is not willing and able to provide a stool, blood, urine and oral sample for this study.
• Participant is not willing and able to complete the questionnaire-based and physical assessments in this study.
• Participant consumes more than one standard alcoholic beverage per day on average and/or consumes more than 4 standard drinks on one occasion.
• Participant smokes or uses vapour-producing devices containing tobacco or other combustible or vaporisable products (including Cannabis in any form) intended for direct inhalation into the lungs.
• Participant has made a major change to diet in the past month prior to enrolment
• Participant has taken any antibiotic medication within the past 3 months.
• Participant has undergone major GI surgery such as bowel resection or other previous bariatric procedure.
• Very senior adults
• Participant is not able to provide own consent or have consent provided for them legally
• Participant requires interpretive language services to communicate in English
• Participant is not willing and able to provide a stool, blood, urine and oral sample for this study.
• Participant is not willing and able to complete the questionnaire-based and physical assessments in this study.
• Participant consumes more than one standard alcoholic beverage per day on average and/or consumes more than 4 standard drinks on one occasion.
• Participant smokes or uses vapour-producing devices containing tobacco or other combustible or vaporisable products (including Cannabis in any form) intended for direct inhalation into the lungs.
• Participant has made a major change to diet in the past month prior to enrolment
• Participant has taken any antibiotic medication within the past 3 months.
• Participant has undergone major GI surgery such as bowel resection or other previous bariatric procedure.
• Senior adult and very senior adult with dementia
• As for each respective group where, a Person Responsible can consent for the participant and
• The participant does not have a diagnosis of dementia from a health professional.