To check the efficacy of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis after premedication with ketorolac and diclofenac potassium

The effect of premedication with single dose of tablet Ketorolac (10mg) given orally, 1 hour prior to initiation of root canal treatment, on the efficacy of Inferior alveolar nerve block (IANB) in patients presenting with symptomatic irreversible pulpitis. The drug will be given to the patient to be taken by oral route under supervision of principal investigator and mouth check will be done to check adherence to the intervention. 1 hour after premedication with the drug, nerve block will be administered by the principal investigator and patient will be asked about feeling of lip numbness to confirm the onset of anesthesia, 15 mins after administration of nerve block. The drug used for IANB will be 1.8 mL of 2% lidocaine containing 1: 200 000 epinephrine (Septodont). The effect of nerve block will be cross checked with cold test using Ethyl chloride spray. If cold test shows negative response then root canal procedure will be initiated after rubber dam isolation. The approximate duration of root canal procedure will be 45 minutes.