Symptomatic Irreversible Pulpitis Clinical Trials

9 recruiting

Frequently Asked Questions

Common questions about Symptomatic Irreversible Pulpitis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 112 of 12 trials

Recruiting
Not Applicable

Short Term Comparative Assessment of MTA and Biodentine in Complete Pulpotomy for Symptomatic Irreversible Pulpitis

Symptomatic Irreversible Pulpitis (SIP)
Dow University of Health Sciences60 enrolled2 locationsNCT07483788
Recruiting
Not Applicable

Postoperative Pain After Root Canal Obturation Using Bioceramic and Calcium Hydroxide Sealers

Symptomatic Irreversible Pulpitis
HITEC-Institute of Medical Sciences50 enrolled1 locationNCT07410780
Recruiting

Do oral steroids or painkillersNon steriodal anti inflammatory drugs (NSAID’S) help dentists numb lower back teeth better in patients with severe toothache?

Acute dental painSymptomatic irreversible pulpitis of mandibular molars
Dr Fawad Ali shah- Khyber college of dentistry60 enrolled1 locationACTRN12626000147381
Recruiting
Not Applicable

Postoperative Pain After Pulpotomy in Children Using Calcium Silicate Cements With and Without Laser Therapy

Symptomatic Irreversible PulpitisSymptomatic Irreversible Pulpitis (SIP)
University of Fujairah46 enrolled1 locationNCT07290049
Recruiting
Not Applicable

A Randomized Controlled Trial Evaluating Whether Pre-operative Trinase Reduces Post-operative Pain in Patients With Symptomatic Irreversible Pulpitis Compared to Placebo, Using VAS Scores and Analgesic Intake Over 48 Hours.

Endodontic DiseaseSymptomatic Irreversible Pulpitis (SIP)Dental Pain+1 more
Fayoum University182 enrolled1 locationNCT07239505
Recruiting
Not Applicable

The Effect of Three Different Medications on Anesthetic Success and Postoperative Pain

Symptomatic Irreversible Pulpitis
Cairo University120 enrolled2 locationsNCT06298383
Recruiting
Not Applicable

Effect of Apical Third Enlargement to Different Taper and Master Apical Preparation Size on Periapical Healing and Postoperative Pain After Primary Single Sitting Non Surgical Root Canal Treatment

Asymptomatic Irreversible Pulpitis
Postgraduate Institute of Dental Sciences Rohtak270 enrolled1 locationNCT07166679
Recruiting
Not Applicable

Intraligamentary vs Inferior Alveolar Nerve Block for Pulpitis: A Randomized Clinical Trial

Local AnesthesiaSymptomatic Irreversible Pulpitis (SIP)Dental Pain+1 more
Aula Dental Avanzada52 enrolled2 locationsNCT07130760
Recruiting
Not Applicable

The Effect of XP-Endo Finisher Activation of Bioceramic Sealer on Postoperative Pain in Mandibular First Molar With Symptomatic Irreversible Pulpitis

Symptomatic Irreversible Pulpitis
Future University in Egypt30 enrolled1 locationNCT06640231
Recruiting
Not Applicable

Postoperative Pain After Full Pulpotomy With TheraCal PT, Biodentin, and MTA

Symptomatic Irreversible Pulpitis (SIP)
Cumhuriyet University51 enrolled2 locationsNCT06880471
Recruiting
Not Applicable

Regenerative Endodontic Therapy in Cases of Irreversible Pulpitis

Symptomatic Irreversible Pulpitis
Shaheed Zulfiqar Ali Bhutto Medical University60 enrolled1 locationNCT06525844
Recruiting
Not Applicable

Effect of Apical Patency and Local Corticosteroid on Pain and Neuropeptides Release in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial

Symptomatic Irreversible PulpitisPostoperative Pain
Suez Canal University40 enrolled1 locationNCT06457828