RecruitingNCT00315380

Longitudinal Study for Eosinophilic Granulomatosis With Polyangiitis

Longitudinal Protocol for Eosinophilic Granulomatosis With Polyangiitis


Sponsor

University of Pennsylvania

Enrollment

700 participants

Start Date

Apr 1, 2006

Study Type

OBSERVATIONAL

Conditions

Summary

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare immune system disorder that causes asthma, an excessive number of eosinophils (a type of white blood cell) in the blood, and the inflammation of blood vessels, or vasculitis. In order to properly treat EGPA, it is critical that the level of disease activity can be determined over the course of the disease. The purpose of this study is to determine new biological markers, or biomarkers, that may be used to assess the severity of this disease in people with EGPA.


Eligibility

Inclusion Criteria2

  • Patients with a diagnosis of eosinophilic granulomatosis with polyangiitis are eligible for the study.
  • Parent or guardian willing to provide informed consent, if applicable

Exclusion Criteria1

  • \- Inability to give informed consent and to sign the consent form

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Locations(13)

University of California San Diego

San Diego, California, United States

National Jewish Health

Denver, Colorado, United States

Brigham and Women's Hospital

Boston, Massachusetts, United States

Mayo Clinic

Rochester, Minnesota, United States

Cleveland Clinic Foundation

Cleveland, Ohio, United States

University of Pennsylvania

Philadelphia, Pennsylvania, United States

University of Pittsburgh

Pittsburgh, Pennsylvania, United States

University of Utah

Salt Lake City, Utah, United States

St. Joseph's Healthcare

Hamilton, Ontario, Canada

Mount Sinai Hospital

Toronto, Ontario, Canada

medius KLINIK KIRCHHEIM

Kirchheim unter Teck, Germany

AOU Meyer IRCCS

Florence, Italy

Imperial College Healthcare NHS Trust/ Imperial College London

London, United Kingdom

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NCT00315380


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