RecruitingNCT01000259

Study of Tumor Tissue Samples From Patients Who Have Undergone Surgery for Advanced Stage III or Stage IV Ovarian Epithelial Cancer

Validation of Tumor-Infiltrating T-Cells as a Biomarker for Advanced Epithelial Ovarian Cancer


Sponsor

Gynecologic Oncology Group

Enrollment

174 participants

Start Date

Sep 1, 2004

Study Type

OBSERVATIONAL

Conditions

Summary

This research study is looking at tumor tissue samples from patients who have undergone surgery for advanced stage III or stage IV ovarian epithelial cancer. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn how tumor infiltrating T cells can predict how patients will respond to treatment.


Eligibility

Sex: FEMALE

Plain Language Summary

Simplified for easier understanding

This study is analyzing tumor tissue samples from women with advanced ovarian cancer who previously participated in chemotherapy trials, to identify molecular markers that predict how well patients respond to platinum and taxol-based chemotherapy. **You may be eligible if...** - You were previously diagnosed with Stage III or IV ovarian cancer - You were enrolled in a Gynecologic Oncology Group (GOG) front-line chemotherapy trial (GOG-0114, GOG-132, GOG-0158, or GOG-0162) and the related GOG-0136 study - Tumor tissue from your primary surgery is available in preserved (paraffin-embedded) form - Demographic data and follow-up information were collected at the time of your original trial **You may NOT be eligible if...** - You do not have preserved tumor tissue available from your original surgery - Adequate follow-up data was not collected during your original trial Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERLaboratory Biomarker Analysis

Samples are analyzed in laboratory studies


Locations(1)

Gynecologic Oncology Group

Philadelphia, Pennsylvania, United States

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NCT01000259


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