RecruitingNCT01427179

Genetic Investigations in Spontaneous Coronary Artery Dissection (SCAD)


Sponsor

Mayo Clinic

Enrollment

2,000 participants

Start Date

May 1, 2011

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of the research is to identify mutations (defects in the genetic blueprint) that cause spontaneous coronary artery dissection (SCAD), in other words, spontaneous tears in blood vessels that supply the heart. Some mutations may be inherited (passed on) from a parent without an apparent blood vessel problem while others may develop for the first time in the affected person.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Men and women able to give informed consent and complete a 2 page questionnaire
  • Diagnosis of one or more episodes of spontaneous coronary artery dissection (SCAD)
  • Biological parent of individual with SCAD
  • Relative with fibromuscular dysplasia, arterial aneurysm, or arterial dissection

Exclusion Criteria1

  • Lack of confirmation of SCAD diagnosis

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Locations(1)

Mayo Clinic

Rochester, Minnesota, United States

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NCT01427179


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