RecruitingNCT07178509

A Study of SCAD Using Stress Contrast Echocardiography

Myocardial Perfusion in Spontaneous Coronary Artery Dissection Using Stress Contrast Echocardiography

Sponsor

Mayo Clinic

Enrollment

50 participants

Start Date

Nov 25, 2025

Study Type

OBSERVATIONAL

Conditions

Spontaneous Coronary Artery Dissection

Summary

This study aims to fill knowledge gaps regarding microvascular perfusion and pressor response to stress among patients with history of spontaneous coronary artery dissection (SCAD) using stress contrast echocardiography.

Eligibility

Min Age: 18 Years

Inclusion Criteria2

Adult \>18 years old
Patient has a history of spontaneous coronary artery dissection (SCAD) OR patient is healthy with no significant medical history

Exclusion Criteria8

Unable to give consent
Allergic or have a history of adverse reaction to dobutamine, the Definity® ultrasound enhancing agent, or atropine.
Has a known or suspected hypersensitivity to perflutren and therefore cannot be given Definity®.
Pregnant.
Unable to interrupt breastfeeding.
Within 3 months of a heart attack.
Severe aortic stenosis.
Severe, uncontrolled hypertension (\>200/110 mmHg at baseline).

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