RecruitingNCT01535430

Assessment of Eloquent Function in Brain Tumor Patients

Assessment of Reorganization and Plasticity of Eloquent Function in Patients With Brain Tumors

Sponsor

University of Nebraska

Enrollment

75 participants

Start Date

Jan 31, 2012

Study Type

OBSERVATIONAL

Conditions

Metastatic Brain Tumor Primary Brain Tumor

Summary

Purpose of the study: AIM 1: Prospectively collect pre-operative \[functional magnetic resonance imaging (fMRI), diffusion tensor imaging (DTI), magnetoencephalography (MEG)\] and intra-operative mapping data in patients with intra-axial brain tumors to assess how well each modality predicts the location of eloquent brain function. In addition, each modality will be compared with the other. AIM 2: Assess reorganization of eloquent brain function and plasticity in patients with intra-axial brain tumors. This will be accomplished by prospectively collecting post-operative mapping studies and neuropsychological tests to compare them to prior mapping studies as stated above.

Eligibility

Min Age: 19 Years

Plain Language Summary

Simplified for easier understanding

This study is assessing how well different brain mapping techniques — both non-invasive (like special MRI scans) and invasive (done during surgery) — can identify critical areas of the brain that control functions like speech and movement in patients with brain tumors near those areas. **You may be eligible if...** - You are 19 years or older - You have a brain tumor (either benign or malignant) located in or near areas of the brain that control important functions like speech or movement - Your doctors believe surgery may be appropriate for your tumor - You are physically and mentally able to participate in the brain mapping procedures **You may NOT be eligible if...** - You have a metal implant or other contraindication that prevents you from having an MRI - You are physically or mentally unable to cooperate with the brain mapping process Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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