RecruitingNot ApplicableNCT01689584

COsegregation of VARiants in Panel of Genes

Study of Family COsegregation of Nucleotide VARiants in the Panel of Genes to Validate Their Use in Genetic Counseling

Sponsor

Institut Curie

Enrollment

11,000 participants

Start Date

Jul 2, 2012

Study Type

INTERVENTIONAL

Conditions

Genetic Predisposition Gene Mutation-Related Cancer

Summary

The aim of the COVAR project is to achieve reliable classification of as many variants of interest as possible from the French OncoGenetics Database (FrOG, https://frog-db.fr/) in order to use them for the genetic counseling. The results obtained through this study will have a major impact on clinical management of the patients and their families conducting in some cases to propose a prophylactic surgery.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying salivary kit for people with gene mutation-related cancer and genetic predisposition. The study is currently recruiting participants at 62 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

GENETICsalivary kit

The saliva samples will be made of selected related (DNA).

Locations(62)

Centre Hospitalier de Bastia

Bastia, Corsica, France

Institut Curie - Saint-Cloud site

Saint-Cloud, Haut de Seine, France

CHU Amiens - Hôpital Nord

Amiens, France

ICO - Centre Paul Papin

Angers, France

Centre Hospitalier d'Angoulème

Angoulême, France

Institut Sainte-Catherine

Avignon, France

CHU Besançon

Besançon, France

Groupe Hospitalier Pellegrin

Bordeaux, France

Institut Bergonié

Bordeaux, France

Centre Hospitalier Jacques Coeur

Bourges, France

CHU Morvan de Brest

Brest, France

Centre François Baclesse

Caen, France

Centre Hospitalier Hôtel Dieu

Chambéry, France

Centre Jean Perrin

Clermont-Ferrand, France

Hôpital Civil de Colmar

Colmar, France

CHU de Dijon

Dijon, France

CHU de Grenoble

Grenoble, France

CHD Vendée

La Roche-sur-Yon, France

Groupe Hospitalier La Rochelle-Ré-Aunis

La Rochelle, France

Hôpital Flaubert

Le Havre, France

Centre Oscar Lambret

Lille, France

Chru Lille

Lille, France

CHU Dupuytren

Limoges, France

Hospices Civils de Lyon

Lyon, France

Centre Léon Bérard

Lyon, France

Institut Paoli Calmettes

Marseille, France

CHU La Timone

Marseille, France

CHU Arnaud de Villeneuve

Montpellier, France

Centre Catherine de Sienne

Nantes, France

Centre Antoine Lacassagne

Nice, France

Centre Hospitalier Georges Renon

Niort, France

CHRU Caremeau

Nîmes, France

Hôpital de la Source

Orléans, France

Hôpital Saint-Antoine

Paris, France

Groupe Hospitalier Pitié-Salpêtrière

Paris, France

Hôpital Tenon

Paris, France

Hôpital Saint-Louis

Paris, France

HEGP

Paris, France

Centre Hospitalier Intercommunal Poissy -Saint Germain-en-Laye

Poissy, France

CHU La Milétrie

Poitiers, France

CHU de Reims

Reims, France

ICC Courlancy

Reims, France

Institut Jean Godinot

Reims, France

Centre Eugène Marquis

Rennes, France

CHU Rennes - Hôpital Sud

Rennes, France

CHU de Rouen

Rouen, France

CHU Saint Etienne

Saint-Etienne, France

ICO - Centre René Gauducheau

Saint-Herblain, France

CLCC Paul Strauss

Strasbourg, France

Hopital de Hautepierre - Hôpital Universitaire

Strasbourg, France

Institut Claudius Regaud - IUCT - Oncopole

Toulouse, France

CHU Bretonneau

Tours, France

CH Simone VEIL

Troyes, France

Centre Hospitalier de Valence

Valence, France

Centre Alexis Vautrin

Vandœuvre-lès-Nancy, France

CHU Nancy - Hôpital Brabois

Vandœuvre-lès-Nancy, France

Gustave Roussy

Villejuif, France

Institut Curie - Paris site

Paris, Île-de-France Region, France

CHU de Pointe à Pitre

Pointe-à-Pitre, Guadeloupe

CHU de Fort de France

Fort-de-France, Martinique

Centre Hospitalier Territorial Gaston Bourret

Noumea, New Caledonia

CHU Sud Réunion Saint-Pierre

Saint-Pierre, Reunion

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NCT01689584

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