Genetic Predisposition Clinical Trials

29 recruiting

Genetic Predisposition Trials at a Glance

51 actively recruiting trials for genetic predisposition are listed on ClinicalTrialsFinder across 6 cities in 29 countries. The largest study group is Not Applicable with 12 trials, with the heaviest enrollment activity in Boston, Milan, and Philadelphia. Lead sponsors running genetic predisposition studies include University Hospital Tuebingen, Boston Children's Hospital, and Abramson Cancer Center at Penn Medicine.

Browse genetic predisposition trials by phase

Treatments under study

About Genetic Predisposition Clinical Trials

Looking for clinical trials for Genetic Predisposition? There are currently 29 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Genetic Predisposition trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Genetic Predisposition clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 51 trials

Recruiting

Vascular Disease Discovery Protocol

Vascular DysfunctionGenetic PredispositionGenetic Mutations
National Heart, Lung, and Blood Institute (NHLBI)1,000 enrolled1 locationNCT03538639
Recruiting

Barriers and Facilitators of Parent-Child Communication in Children With Cancer Predisposition

Genetic Predisposition
St. Jude Children's Research Hospital125 enrolled1 locationNCT05849155
Recruiting

Outcomes of Health Care Transition for AYA With a Cancer Predisposition

Genetic Predisposition
St. Jude Children's Research Hospital56 enrolled1 locationNCT07456904
Recruiting
Not Applicable

Enhancing Information Management for Young Adults After Genetic Cancer Risk Testing

Genetic Predisposition to DiseaseGenetic Predisposition
Dana-Farber Cancer Institute40 enrolled1 locationNCT05759143
Recruiting
Not Applicable

Germline Testing for Predisposition to Myeloid Malignancies

Genetic Predisposition to DiseaseMyeloid MalignancyMyeloid Hematological Malignancies
Christopher Reilly200 enrolled1 locationNCT07112287
Recruiting

Pancreatic Cancer Early Detection Consortium

Pancreatic Ductal AdenocarcinomaPancreas CancerGenetic Predisposition+1 more
Arbor Research Collaborative for Health20,000 enrolled60 locationsNCT04970056
Recruiting

Rare Tumors and Cancer Predisposition in Individuals and Families

CancerGenetic Predisposition to CancerHereditary Neoplasms+1 more
National Cancer Institute (NCI)500 enrolled2 locationsNCT05350761
Recruiting
Phase 4

GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH

Genetic PredispositionType 2 DiabetesMetabolic Diseases
Massachusetts General Hospital125 enrolled1 locationNCT06003153
Recruiting
Not Applicable

EXOME Analysis Position in the Strategy of Genetic Predisposition Factors Identification in Early-onset Cancer

CancerGenetic Predisposition
Centre Georges Francois Leclerc613 enrolled6 locationsNCT04141462
Recruiting
Phase 1

Assessment of Topical Minoxidil on Intraoperative Flap Perfusion and Cutaneous Flap Viability in Breast Recon

Breast ReconstructionGenetic PredispositionPerfusion; Complications+1 more
Duke University25 enrolled1 locationNCT07264790
Recruiting

Prospective Multicenter Registry of Gender, Diversity and Inclusion (GEDI) of Women With Acute Coronary Syndrome

Acute Coronary SyndromeGenetic PredispositionGender
IRCCS San Raffaele100 enrolled4 locationsNCT06441942
Recruiting

Helix Research Network

Genetic Predisposition to DiseaseGenetics Disease
Helix, Inc2,000,000 enrolled14 locationsNCT06057181
Recruiting
Phase 2

Microbiome and Association With Implant Infections

Breast CancerBreast Cancer FemaleGenetic Predisposition to Disease
University of California, San Francisco200 enrolled1 locationNCT05020574
Recruiting

The China Neonatal Genomes Project

Genetic Predisposition to DiseaseNewbornHereditary Disease+1 more
Children's Hospital of Fudan University100,000 enrolled1 locationNCT03931707
Recruiting

Assesment of Multiomics Profiles in Health and Disease.

Genetic Predisposition to Disease
The Institute of Molecular and Translational Medicine, Czech Republic1,100 enrolled1 locationNCT04427163
Recruiting

Healthy Volunteers Study

Ovarian CancerGenetic Predisposition to Disease
Abramson Cancer Center at Penn Medicine50 enrolled1 locationNCT06962059
Recruiting

VIGOR: Virtual Genome Center for Infant Health

Genetic Predisposition to DiseaseGenetics DiseaseGenetics/Birth Defects
Boston Children's Hospital750 enrolled10 locationsNCT05205356
Recruiting
Not Applicable

Expression of Genes Relating Hypertension and Efficacy of 4-7-8 Breathing Control on Reducing Blood Pressure

Genetic Predisposition to DiseaseBreathing, Mouth
Burapha University200 enrolled1 locationNCT07018128
Recruiting

Precision Medicine in the Prostate Cancer Care Pathway

Prostate CancerGenetic Predisposition
Institute of Cancer Research, United Kingdom3,000 enrolled1 locationNCT04763317
Recruiting
Not Applicable

PTX3-targeted Antifungal Prophylaxis

Acute Myeloid LeukemiaGenetic PredispositionCandidiasis+2 more
Bochud Pierre-Yves410 enrolled9 locationsNCT03828773