Rare Kidney Stone Consortium Biobank

This study is a biobank (a collection of biological samples and data) for people with rare kidney stone diseases including primary hyperoxaluria (PH), Dent disease, APRT deficiency, and cystinuria. Researchers collect urine, blood, and tissue samples to better understand these conditions and improve future treatments. You may be eligible if: - You have been diagnosed with primary hyperoxaluria (type 1, 2, or 3) confirmed by liver biopsy, genetic testing, or urine/blood tests - You have been diagnosed with Dent disease confirmed by genetic mutation or specific lab results - You have been diagnosed with APRT deficiency confirmed by enzyme activity or genetic testing - You have been diagnosed with cystinuria confirmed by stone analysis or urine test - You are a family member (relative) of someone with any of the above conditions - You were previously enrolled in a related Mayo Clinic study (#80-04) You may NOT be eligible if: - You form kidney stones but do NOT have a confirmed diagnosis of PH, cystinuria, Dent disease, or APRT deficiency - You are unwilling or unable to provide consent Talk to your doctor to see if this trial is right for you.