Germ Cell Tumor and Testicular Tumor DNA Registry
Memorial Sloan Kettering Cancer Center
1,000 participants
Jan 1, 2014
OBSERVATIONAL
Conditions
Summary
This study is being done to create a registry to help us learn more about germ cell tumors (GCT) and other testicular tumors. The registry will include people with these tumors and also relatives and unrelated people without these tumors. This study will help us learn more about the prevention, diagnosis, treatment and outcome of these tumors. Studying relatives of patients and people unrelated to patients with GCT and other testicular tumors will help us understand why some people get these tumors and why some people don't.
Eligibility
Inclusion Criteria14
- Case Cohort
- Must be ≥ 18 years of age AND
- Must be an English-speaker AND
- Must have a diagnosis or suspicion of germ cell tumor and/or a testicular mass
- Family Member Cohort
- Must be ≥ 18 years of age AND
- Must be an English-speaker AND
- Must be a blood relative of the proband. Family members of probands are eligible. These individuals need not have a diagnosis of GCT-TT, as they will be used for segregation analysis of suspected variants found in the proband.
- Control Cohort
- Must be ≥ 18 years of age AND
- Must be an English-speaker AND
- Must not have a personal history of cancer, with the exception of non-melanoma skin cancer, AND
- Must not have a family history of germ cell tumor or testicular tumor AND
- Must not be a blood relative of controls enrolled in this study
Interventions
A sample of blood or saliva will be obtained for DNA extraction. Approximately 2-4 tubes of blood will be collected or one tablespoon of saliva. If a participant has already provided a DNA sample for another MSKCC IRB approved protocol, they may not need to provide an additional sample.
Locations(8)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT02099734