RecruitingNot ApplicableNCT02216500

Ketogenic Therapy Effects on Electrical and Metabolic Abnormalities in Epilepsy

Precision Ketogenic Therapy Effects on Electrical and Metabolic Abnormalities in Epilepsy

Sponsor

University of Florida

Enrollment

400 participants

Start Date

Sep 1, 2006

Study Type

INTERVENTIONAL

Conditions

Seizures

Summary

Approximately a fourth of children with seizures do not respond adequately to available therapy. Ketogenic therapy has a long history as treatment for intractable epilepsy, but there is no agreement concerning how it works and what is the best way to administer it. This natural history study will collect data pertaining to both questions.

Eligibility

Max Age: 50 Years

Inclusion Criteria3

Patients whose physician has prescribed the ketogenic diet
Patients with lab tests consistent with the ability to metabolize a high fat and low carbohydrate diet
Patients that can be compliant with administration of the therapy and with record keeping.

Exclusion Criteria2

Patients with lab tests consistent with the inability to metabolize a high fat and low carbohydrate diet
Patients at risk of being non-compliant with administration of the therapy and with record keeping

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Interventions

DIETARY_SUPPLEMENTKetogenic Therapy

Ketogenic Therapy is based on a ratio of fat: protein+carbohydrate in which protein intake is adequate, fat intake is high, and carbohydrate intake is minimal.