Seizures Clinical Trials

31 recruiting

Seizures Trials at a Glance

45 actively recruiting trials for seizures are listed on ClinicalTrialsFinder across 6 cities in 35 countries. The largest study group is Not Applicable with 11 trials, with the heaviest enrollment activity in Madrid, Tampa, and Los Angeles. Lead sponsors running seizures studies include Supernus Pharmaceuticals, Inc., NaviFUS Corporation, and Children's Hospital of Fudan University.

Browse seizures trials by phase

Treatments under study

About Seizures Clinical Trials

Looking for clinical trials for Seizures? There are currently 31 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Seizures trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Seizures clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 45 trials

Recruiting
Phase 3

A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures

Stereotypical Prolonged Seizures
UCB Biopharma SRL350 enrolled183 locationsNCT05077904
Recruiting
Phase 2

Safety and Tolerability Study of SPN-817 in Adult Patients With Treatment Resistant Epilepsy

EpilepsySeizures, Epileptic
Supernus Pharmaceuticals, Inc.60 enrolled10 locationsNCT05518578
Recruiting
Not Applicable

A Pilot Study to Evaluate the Efficacy and Safety of NaviFUS™ System Neuromodulating Treatment for Patients With Drug Resistant Epilepsy

EpilepsyDrug Resistant EpilepsyEpilepsy, Temporal Lobe+1 more
NaviFUS Corporation16 enrolled1 locationNCT06492720
Recruiting
Phase 1Phase 2

A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy

EpilepsyDrug Resistant EpilepsySeizures, Focal
NaviFUS Corporation8 enrolled3 locationsNCT06388707
Recruiting

Investigating Epilepsy: Screening and Evaluation

EpilepsySeizuresEpilepsy, Temporal Lobe+1 more
National Institute of Neurological Disorders and Stroke (NINDS)1,000 enrolled1 locationNCT03478852
Recruiting
Phase 1

A Study to Evaluate the Efficacy and Safety of Cannabidiol Oral Solution (CBD-OS [GWP42003-P, JZP926]) for the Treatment of Focal-Onset Seizures

Focal Seizures
Jazz Pharmaceuticals100 enrolled23 locationsNCT07233239
Recruiting
Phase 2

Prophylactic Anti-Seizure Medication vs No Anti-Seizure Medication for Patients With Primary Motor Cortex Brain Metastases

Brain Metastases, AdultBrain Metastases From Non-small Cell Lung Cancer (NSCLC)Brain Metastases From Extra-cranial Solid Tumors+2 more
Ayal A. Aizer, MD150 enrolled1 locationNCT07130786
Recruiting
Not Applicable

A Multi-site Feasibility Clinical Trial of Retraining and Control Therapy (ReACT), a Mind and Body Treatment for Pediatric Functional Seizures

Convulsion, Non-EpilepticFunctional Seizures
University of Alabama at Birmingham108 enrolled1 locationNCT05819268
Recruiting

Etiology and Treatment of Neonatal Seizure

SeizuresSeizure DisorderSeizure Newborn+1 more
Children's Hospital of Fudan University2,000 enrolled1 locationNCT03822741
Recruiting
Not Applicable

Cognitive Rehabilitation for Veterans With PNES

Psychogenic Nonepileptic Seizures (PNES)
VA Office of Research and Development47 enrolled1 locationNCT07316543
Recruiting
Phase 3

A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

Primary Generalized Tonic-Clonic Seizures
Xenon Pharmaceuticals Inc.160 enrolled138 locationsNCT05667142
Recruiting
Phase 3

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)

Focal Onset Seizures
Xenon Pharmaceuticals Inc.360 enrolled94 locationsNCT05716100
Recruiting
Phase 3

Short Versus Long-term Levetiracetam in Brain Tumors

SeizuresBrain TumorsAntiepileptics+1 more
Tata Memorial Centre604 enrolled2 locationsNCT06442748
Recruiting
Phase 3

LEvetiracetam to Prevent Seizures in Symptomatic Alzheimer's Disease in Adults With Down Syndrome

EpilepsyAlzheimer DiseaseSeizures+7 more
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau120 enrolled5 locationsNCT07234695
Recruiting
Not Applicable

Modulating Movement Intention Via Cortical Stimulation

SeizuresSeizure DisorderPsychogenic Movement Disorder
NYU Langone Health30 enrolled1 locationNCT03233399
Recruiting
Not Applicable

Acute Effects of Focused Ultrasound Modulation on EEG Behavior in Status Epilepticus Patients

Seizures
Yale University10 enrolled1 locationNCT05784805
Recruiting
Not Applicable

Ear-Seizure Detection (EarSD) Study

EpilepsySeizures
Felicia Chu40 enrolled2 locationsNCT06598189
Recruiting
Not Applicable

Oxygen Toxicity: Mechanisms in Humans

SeizuresHypercapniaOxygen Toxicity
Duke University62 enrolled1 locationNCT05761756
Recruiting
Phase 2

A Study to Evaluate Efficacy and Safety of Perampanel Administered as an Adjunctive Therapy in Pediatric Participants With Childhood Epilepsy

Pediatric Epileptic SyndromePartial-onset Seizures
Eisai Inc.100 enrolled49 locationsNCT04015141
Recruiting
Phase 2

SPN-817 Open-Label Extension Study in Adults With Focal Onset Seizures

Focal Onset Seizures
Supernus Pharmaceuticals, Inc.100 enrolled1 locationNCT07141329