Cardiovascular Health Improvement Project

This trial is studying the genetic and health factors that lead to problems with the aorta (the main artery in the body) and related blood vessels, including aortic aneurysms, to help improve diagnosis and treatment. **You may be eligible if...** - You are 18 or older (or younger with parental consent) and willing to participate - You have been diagnosed with aortic disease linked to a known or suspected inherited condition - You have an aortic aneurysm with no known cause - You have an unusual or rare blood vessel condition in the aorta or its main branches - You have a family history of aortic or blood vessel disease - You have another form of cardiovascular disease - You are a healthy person willing to serve as a comparison subject **You may NOT be eligible if...** - You are unwilling or unable to sign the consent form Talk to your doctor to see if this trial is right for you.