Aortic Aneurysm Clinical Trials

128 recruitingLast updated: June 13, 2026

There are 128 actively recruiting aortic aneurysm clinical trials across 28 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4, Phase 1, Early Phase 1. Top locations include Philadelphia, Pennsylvania, United States, Boston, Massachusetts, United States, Cleveland, Ohio, United States. Updated daily from ClinicalTrials.gov.


Aortic Aneurysm Trials at a Glance

128 actively recruiting trials for aortic aneurysm are listed on ClinicalTrialsFinder across 6 cities in 28 countries. The largest study group is Not Applicable with 62 trials, with the heaviest enrollment activity in Philadelphia, Boston, and Cleveland. Lead sponsors running aortic aneurysm studies include W.L.Gore & Associates, Mayo Clinic, and Lifetech Scientific (Shenzhen) Co., Ltd..

Browse aortic aneurysm trials by phase

Treatments under study

About Aortic Aneurysm Clinical Trials

Looking for clinical trials for Aortic Aneurysm? There are currently 25 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Aortic Aneurysm trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Aortic Aneurysm clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 128 trials

Recruiting
Not Applicable

EndoVascular Aortic Repair With Sac Embolization for the Prevention of Type II Endoleaks (the EVAR-SE Study)

Abdominal Aortic AneurysmEndoleak
Univ.-Prof. Dr. Dr. med. Daniela Branzan100 enrolled1 locationNCT05665101
Recruiting
Phase 1Phase 2

HEART: Pilot Randomized Controlled Trial

Thoracic Aortic Aneurysm
Mayo Clinic50 enrolled1 locationNCT07483177
Recruiting

European Aortic Data Collection Project

Complex Abdominal Aortic AneurysmThoracoabdominal Aortic AneurysmAortic Arch Aneurysm+1 more
Cook Research Incorporated600 enrolled18 locationsNCT05896397
Recruiting
Not Applicable

Nectero EAST System Retreatment Study

AAA - Abdominal Aortic AneurysmAorta AneurysmDilation Aorta
Nectero Medical, Inc.10 enrolled2 locationsNCT07505082
Recruiting
Phase 2Phase 3

Nectero EAST System Clinical Study

Abdominal Aortic Aneurysm
Nectero Medical, Inc.400 enrolled39 locationsNCT06001918
Recruiting
Not Applicable

Thoracoabdominal Artery Stent Graft System Exploratory Study

Thoracoabdominal Aortic Aneurysms
Lifetech Scientific (Shenzhen) Co., Ltd.11 enrolled1 locationNCT06710938
Recruiting

Molecular Imaging of the Underlying Mechanism of Vessel Wall Inflammation Using Positron Emission Tomography (PET/CT)

Abdominal Aortic Aneurysm
University of Pennsylvania30 enrolled1 locationNCT07548099
Recruiting
Not Applicable

ShOrt neCK AAA RAndomized Trial - ESAR and FEVAR: SOCRATES

Aortic Aneurysm, Abdominal
FCRE (Foundation for Cardiovascular Research and Education)204 enrolled33 locationsNCT04503395
Recruiting

Incidence of Major Complication in Case of Thoracic Aortic Aneurysm

Thoracic Aortic Aneurysm
University Hospital, Lille320 enrolled1 locationNCT05395598
Recruiting
Not Applicable

University of Utah PS-IDE: Physician Modified Endovascular Grafts for the Treatment of Elective, Symptomatic or Ruptured Juxtarenal Aortic Aneurysms

Juxtarenal Abdominal Aortic Aneurysm
Cali Johnson15 enrolled1 locationNCT07065760
Recruiting

Patient-Reported Quality of Life After Open Surgery for Complex Abdominal Aortic Aneurysms: A Prospective Study

Complex Abdominal Aortic Aneurysms
Prouse Giorgio125 enrolled2 locationsNCT07580443
Recruiting

Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With ACTIVE CONTROL System Performance

Aneurysm ThoracicVascular DiseaseDissection+5 more
W.L.Gore & Associates1,500 enrolled34 locationsNCT06658730
Recruiting
Not Applicable

Comparison of EVAR and ESAR for Infrarenal Aortic Aneurysms With a Wide Proximal Neck

Aortic Aneurysm, Abdominal
Rijnstate Hospital300 enrolled36 locationsNCT05484115
Recruiting

TAMBE Japan Post-Marketing Surveillance

Pararenal Aortic AneurysmThoracoabdominal Aortic Aneurysm
W.L.Gore & Associates100 enrolled5 locationsNCT07147569
Recruiting

Coagulation Factors Alterations in Patients Undergoing Complex Thoraco-abdominal Aortic Aneurysm Repair

Platelet ActivationThoraco-abdominal Aortic Aneurysm RepairCoagulation Factors Alterations
University of Thessaly58 enrolled2 locationsNCT06432387
Recruiting
Not Applicable

AAA-SHAPE Pivotal Trial: Abdominal Aortic Aneurysm Sac Healing and Prevention of Expansion

Aortic Aneurysm, Abdominal
Shape Memory Medical, Inc.180 enrolled49 locationsNCT06029660
Recruiting
Not Applicable

Physician Modified Endograft For Complex Aortic Aneurysm Repair

Complex Abdominal Aortic AneurysmJuxtarenal Aortic AneurysmPararenal Aortic Aneurysm+1 more
University of California, Davis40 enrolled1 locationNCT05339061
Recruiting

Aortopathy Relationship To Imagery and Kinocardiography Features (ARTIK)

Aortic Valve DiseaseAortic Aneurysm
Université Libre de Bruxelles180 enrolled1 locationNCT06286358
Recruiting

Cardiovascular Health Improvement Project

Heart FailureCardiovascular DiseasesAortic Aneurysm+2 more
University of Michigan15,000 enrolled1 locationNCT02306200
Recruiting
Not Applicable

Physician-Modified Fenestrated and Branched Aortic Endografting for TAAA

Aortic Aneurysm, Thoracoabdominal
Yale University80 enrolled2 locationsNCT02989948