RecruitingNCT02420470

The Early Warning System for the Diabetic Encephalopathy

The Early Warning System for the Central Nervous System Micro-structure Alterations During Early Diabetes Based on the Multi-mode MRIs

Sponsor

Tang-Du Hospital

Enrollment

300 participants

Start Date

Apr 1, 2015

Study Type

OBSERVATIONAL

Conditions

Diabetes Mellitus, Type 2 Mild Cognitive Impairment Metabolic Syndrome X

Summary

Diabetes( mainly type II diabetes )lead to the central nervous system (CNS) function impairment, especially the mild cognitive impairment that increased the risk of progression to dementia.The primary objectives are defined according to a hierarchical design: i) to tailor and apply multi-parametric, functional MRI techniques to identify cerebral abnormalities (cerebral biomarkers) in type 2 diabetes mellitus and prodromal diabetes mellitus ; ii) to assess whether these cerebral biomarkers are associated with cognitive decrements;iii) to follow up with the putative prediabetic condition patients to verify whether they can transform into diabetes.

Eligibility

Min Age: 40 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating whether diabetes affects how the brain works — even before obvious memory problems appear — by using specialized brain scans to detect early warning signs of diabetes-related brain changes. **You may be eligible if...** - You do not have dementia - You have at least 6 years of education - Your blood sugar levels match the group requirements for the study (either with or without diabetes, depending on the group) - You are willing to provide informed consent **You may NOT be eligible if...** - You are pregnant - You have a serious brain disease - You have a condition that prevents you from having an MRI scan (such as a metal implant or pacemaker) - You are unlikely to follow through with the study requirements - Your brain scan images would be too poor quality to analyze Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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