Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors

This trial is testing a type of stem cell transplant from a half-matched family donor (called a haploidentical transplant) combined with a bone-strengthening drug (Zometa) for children and young people with blood cancers or solid tumors who don't have a perfectly matched donor available. **You may be eligible if...** - You are a child or young adult with a blood cancer (like leukemia or lymphoma) or certain solid tumors (like neuroblastoma or sarcoma) that has relapsed or not responded to treatment - You do not have a fully matched bone marrow donor available, or finding one would take too long - A half-matched family member is available to donate stem cells - Your heart, liver, and kidneys are functioning adequately - You have no uncontrolled infections - Your general health score is 60 or higher (on standard medical performance scales) **You may NOT be eligible if...** - You are pregnant or breastfeeding - You are HIV-positive - You have had a prior organ transplant (not stem cell) - You have heart failure or a serious uncontrolled infection - You have a serious unrelated illness that significantly increases your transplant risk - You are enrolled in another clinical trial that might affect results Talk to your doctor to see if this trial is right for you.