POTS Adrenergic Ab (CIHR Aims #1&2)
The Pathophysiological Role of Adrenergic Antibodies in Postural Tachycardia Syndrome (Aims #1&2)
University of Calgary
125 participants
Jan 1, 2016
OBSERVATIONAL
Conditions
Summary
Objective: In this pilot study, we will test the hypothesis that patients with POTS (age 18-60 years) will have a higher percentage of functional antibodies to adrenergic receptors compared with control subjects without POTS.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
incremental small doses of IV phenylephrine to find the dose that transiently raises systolic blood pressure by 25 mmHg
incremental small doses of IV isoproterenol to find the dose that transiently raises heart rate by 25 bpm
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT02673996