RecruitingNCT02688517

Targeted Genomic Analysis of Blood and Tissue Samples From Patients With Cancer

Targeted Genomic Analysis of Human Cancers


Sponsor

Rutgers, The State University of New Jersey

Enrollment

1,100 participants

Start Date

Feb 1, 2013

Study Type

OBSERVATIONAL

Conditions

Summary

This research trial studies the use of targeted genomic analysis of blood and tissue samples from patients with cancer. Genomic sequencing is a laboratory method that is used to determine the entire genetic makeup of a specific organism or cell type. Genomic sequencing can be used to find changes in areas of the genome that may be important in the development of cancer. It may also help doctors improve ways to diagnose and treat patients with rare cancers with poor prognosis or lack of effective therapy.


Eligibility

Min Age: 1 Year

Inclusion Criteria4

  • Karnofsky/Lansky performance score >= 30
  • A signed written informed consent
  • Evaluation in surgical/medical/radiation oncology/radiology clinic, with a history of biopsy-confirmed diagnosis of cancer of rare histology and/or poor prognosis with standard therapy; priority will be given to rare cancers with poor prognosis and lack of effective standard therapy; study principal investigator (PI) or designee will review and approve each case before enrollment
  • Paraffin blocks of the patient's tumor tissue are available and accessible for analysis

Exclusion Criteria2

  • Karnofsky/Lansky performance score < 30
  • Life expectancy < 3 months

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Interventions

OTHERCytology Specimen Collection Procedure

Undergo collection of blood samples

OTHERLaboratory Biomarker Analysis

Correlative studies


Locations(11)

Ocean Medical Center

Brick, New Jersey, United States

Bayshore Community Hospital

Holmdel, New Jersey, United States

RWJBarnabas Health - Jersey City Medical Center, Jersey City

Jersey City, New Jersey, United States

Southern Ocean County Medical Center

Manahawkin, New Jersey, United States

Morristown Medical Center

Morristown, New Jersey, United States

Jersey Shore Medical Center

Neptune City, New Jersey, United States

Rutgers Cancer Institute of New Jersey

New Brunswick, New Jersey, United States

Riverview Medical Center/Booker Cancer Center

Red Bank, New Jersey, United States

Riverview Medical Center

Red Bank, New Jersey, United States

Overlook Hospital

Summit, New Jersey, United States

University of Wisconsin Hospital and Clinics

Madison, Wisconsin, United States

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NCT02688517


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