Frameless Stereotactic Radiosurgery for Intact Brain Metastases

This study is testing frameless stereotactic radiosurgery — a highly precise, non-invasive radiation treatment that delivers focused beams directly to brain tumors — for patients whose cancer has spread to the brain from another part of the body. **You may be eligible if...** - You are 18 or older with a life expectancy of at least 3 months - You have 1 to 5 brain tumors confirmed by MRI that spread from a cancer elsewhere in your body - Each brain tumor is no larger than 3 cm (about 1.2 inches) in diameter - At least one tumor is large enough to be measured (at least 1 cm across) - Women of childbearing age must have a negative pregnancy test before the CT planning scan **You may NOT be eligible if...** - You have more than 5 brain tumors - Any tumor is larger than 3 cm in diameter - You have cancer spread along the fluid surrounding the brain (leptomeningeal disease) - You are pregnant - You are not well enough to complete treatment and follow-up appointments Talk to your doctor to see if this trial is right for you.