RecruitingNCT02798731

Physiologic Assessment of Microvascular Function in Heart Transplant Patients

Physiologic Assessment of Microvascular Function and Its Impact on Cardiac Allograft Vasculopathy in Heart Transplant Patients: Prospective Registry and Pilot Study


Sponsor

Samsung Medical Center

Enrollment

200 participants

Start Date

May 1, 2016

Study Type

OBSERVATIONAL

Conditions

Summary

The aim of the study is to evaluate the impact of early microvascular disease assessed by coronary physiologic indices such as fractional flow reserve (FFR), coronary flow reserve (CFR), index of microvascular resistance (IMR) on future occurrence of cardiac allograft vasculopathy (CAV) in heart transplant recipients.


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Inclusion Criteria2

  • Subject over age of 18
  • Patients received heart transplant

Exclusion Criteria7

  • Patients with cardiogenic shock
  • Patients with unstable vital sign that precludes coronary angiography
  • Patients with major bleeding in last 3 months
  • Patients with active bleeding
  • Patients with coagulopathy
  • Patients with severe valvular heart disease
  • Patients who refused to provide informed consent

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Locations(1)

Samsung Medical Center

Seoul, South Korea

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NCT02798731


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