MARINER Trial: Multiparametric Cardiac PET for CAV Surveillance After Heart Transplantation
Multiparametric Cardiac Positron Emission Tomography for Cardiac Allograft Vasculopathy Surveillance After Heart Transplantation
Ottawa Heart Institute Research Corporation
576 participants
Jan 8, 2024
INTERVENTIONAL
Conditions
Summary
Cardiac allograft vasculopathy (CAV) is a common complication affecting heart transplant patients. This condition causes narrowing of the heart arteries leading to graft dysfunction. Surveillance for CAV is vital; however an ideal approach has not been established. The goal of this study is to assess whether noninvasive positron emission tomography (PET) based surveillance is non-inferior to invasive coronary angiography (ICA) surveillance.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
Patients will undergo annual CAV surveillance with ICA
Patients will undergo annual CAV surveillance with PET
Locations(5)
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NCT06089486