RecruitingNot ApplicableNCT02947971

Pilot Study for TCE Imaging of the Esophagus Using an OFDI Capsule With a Compact Imaging System

Pilot Study for TCE (Tethered Capsule Endomicroscopy) Imaging of the Esophagus Using an OFDI (Optical Frequency Domain Imaging) Capsule With a Compact Imaging System


Sponsor

Massachusetts General Hospital

Enrollment

120 participants

Start Date

Apr 15, 2016

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this research is to test a distal scanning capsule and a compact redesigned version of the OFDI imaging system in healthy and BE participants to assess ease of use, safety and feasibility in preparation for its use in a multicenter clinical trial.


Eligibility

Min Age: 14 YearsMax Age: 85 Years

Inclusion Criteria4

  • Participants 18 years and older with a previous diagnosis of GERD
  • Health participants over the age of 18 but less than 85 years of age
  • Participants must be able to give informed consent
  • Participants must have no solid food for 4 hours prior to the procedure, and only clear liquids for 2 hours prior to the procedure.

Exclusion Criteria5

  • Participants over 85 years of age
  • Participants with the inability to swallow pills and capsules.
  • Participants with a strong gag reflex
  • Esophageal fistula and/or esophageal strictures with a stricture diameter that is smaller than the diameter of the capsule.
  • Participants who are pregnant. In case of women of child bearing age, we will ask them if they are pregnant and if unsure; ask them to take a pregnancy test.

Interventions

DEVICEExperimental OFDI Imaging

Imaging of the esophagus with a compact OFDI system and distal scanning catheter


Locations(1)

Massachusetts General hospital

Boston, Massachusetts, United States

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NCT02947971


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