RecruitingNot ApplicableNCT06748911

Navicam for Detection of Barrett's Esophagus

Use of a Detachable String Capsule for Evaluation of Barrett's Esophagus

Sponsor

Mayo Clinic

Enrollment

57 participants

Start Date

Feb 20, 2025

Study Type

INTERVENTIONAL

Conditions

Barrett's Esophagus

Summary

Using a non-invasive capsule system to achieve optimal viewing angles of the esophagus for detection of Barrett's esophagus

Eligibility

Min Age: 22 Years

Plain Language Summary

Simplified for easier understanding

This study is evaluating a swallowable capsule camera called Navicam as a way to detect Barrett's esophagus — a condition where the lining of the food pipe changes due to long-term acid reflux, which can sometimes lead to cancer. The study wants to see if this camera pill is a comfortable, effective alternative to standard endoscopy. **You may be eligible if...** - You are 22 or older - You have had a standard endoscopy within the past year - You have already been diagnosed with Barrett's esophagus, OR you have chronic acid reflux (GERD) with at least 3 additional risk factors meeting Barrett's screening guidelines **You may NOT be eligible if...** - You have a tumor in your throat, esophagus, or stomach junction - You have difficulty swallowing - You have an active, significant narrowing in your esophagus - You are unable to read or understand the consent form Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICENaviCam Detachable String Capsule

Subjects will swallow the NaviCam capsule with 20 ml water while positioned in the upright position. Once the capsule reaches the gastric cardia, the string will slowly be pulled up to systematically inspect the Z-line and upper, middle, and lower thirds of the esophagus guided by real-time viewing and by moving the capsule solely with the tether. Images will be captured at a rate of 2 frames per second.