Chemoradiation Versus Esophagectomy for Locally Advanced Esophageal Cancer

This study is comparing two treatments for locally advanced esophageal (food pipe) cancer: a combination of chemotherapy and radiation therapy versus surgery to remove the tumor, to see which leads to better outcomes. **You may be eligible if...** - You are of Chinese ethnicity - You have been diagnosed with squamous cell cancer of the esophagus (a specific type of food-pipe cancer) - Your tumor is in the middle or lower part of the esophagus - Surgery to remove the tumor is possible (or potentially possible) - Your cancer stage is within certain locally advanced categories (no distant spread) **You may NOT be eligible if...** - Cancer has spread to distant organs (like the liver or lungs) - Cancer has grown into the windpipe, major blood vessels, or nerves near the voice box - You have serious other medical conditions or are too unwell to safely have chest surgery Talk to your doctor to see if this trial is right for you.