RecruitingPhase 1NCT07054684
Study of BHV-1400 in IgA Nephropathy
An Open-Label Biomarker Study of BHV-1400 in IgA Nephropathy
Sponsor
Biohaven Therapeutics Ltd.
Enrollment
20 participants
Start Date
Jul 30, 2025
Study Type
INTERVENTIONAL
Conditions
Summary
The purpose of this study is to determine if BHV-1400 is a safe and tolerable treatment in participants with IgA Nephropathy (IgAN).
Eligibility
Min Age: 18 YearsMax Age: 65 Years
Plain Language Summary
Simplified for easier understanding
This trial tests a new drug called BHV-1400 in people with IgA nephropathy — a kidney disease where a protein called IgA builds up in the kidneys and causes inflammation and progressive kidney damage. BHV-1400 is designed to reduce the IgA deposits and slow down kidney damage.
**You may be eligible if...**
- You have been diagnosed with IgA nephropathy confirmed by kidney biopsy
- You are experiencing signs of progressive kidney damage (such as protein in the urine)
- You meet the health criteria to take part in the study
**You may NOT be eligible if...**
- Your IgA nephropathy is secondary (caused by another condition like liver disease or inflammatory bowel disease)
- Your kidney disease is caused by something other than IgA nephropathy
- You have severely impaired kidney function or are on dialysis
Talk to your doctor to see if this trial is right for you.
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
DRUGBHV-1400
BHV-1400 is delivered subcutaneously (SC)
Locations(12)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07054684
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