RecruitingNCT03125655

Regulation of Inflammatory Genes in Psoriasis


Sponsor

University of Alabama at Birmingham

Enrollment

13 participants

Start Date

Apr 22, 2014

Study Type

OBSERVATIONAL

Conditions

Summary

Psoriasis is a chronic and recurrent skin disorder characterized by marked inflammatory changes in the skin. An extensive cytokine network including generated by activated dendritic cells and T cells mediates the formation of psoriatic lesions. These immune-response parameters can be used as markers in the severity and management of the disease after further in-depth studies.


Eligibility

Min Age: 19 YearsMax Age: 99 Years

Inclusion Criteria3

  • Clinical diagnosis of psoriasis
  • Must be age 19 or older.
  • Must be Fitzpatrick skin type I, II, III, IV, V, VI.

Exclusion Criteria4

  • Subjects who do not have photosensitive disease and are not on photosensitizing medications.
  • Subjects with a history of keloids (who are more likely to develop hypertrophic scars following skin biopsy).
  • Subjects who have an allergy to local anesthetics, antibiotics and/or anticoagulants.
  • Subjects who are pregnant.

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Interventions

DIAGNOSTIC_TESTInflammatory markers

Locations(1)

The Kirklin Clinic

Birmingham, Alabama, United States

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NCT03125655


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