RecruitingNot ApplicableNCT03145077

Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Diagnosing Osteoradionecrosis in Patients With Head and Neck Cancer That Is Primary, Has Come Back, or Has Spread to Other Places in the Body

Using Magnetic Resonance Imaging (MRI) to Assess Mandibular and Soft Tissue Responses to Radiation Therapy


Sponsor

M.D. Anderson Cancer Center

Enrollment

1,400 participants

Start Date

Mar 21, 2017

Study Type

INTERVENTIONAL

Conditions

Summary

This trial studies how well dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) works in diagnosing osteoradionecrosis in patients with head and neck cancer that is primary, has come back, or has spread to other places in the body who are undergoing radiation therapy. DCE-MRI may help doctors to predict osteoradionecrosis in patient with head and neck cancer undergoing radiation therapy.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a special type of MRI scan (called DCE-MRI) to see if it can detect a painful condition called osteoradionecrosis — bone damage caused by radiation therapy — in patients who have been treated for head and neck cancer. **You may be eligible if...** - You have been diagnosed with a head or neck cancer (confirmed by biopsy) - You have already received external beam radiation therapy to the head or neck area, with or without chemotherapy - Your overall health and functioning are good (ECOG score 0-2) - You are willing to follow the study schedule for the full duration **You may NOT be eligible if...** - You have not had external beam radiation therapy for head and neck cancer - Your health is too poor for the required procedures - You are unable to complete MRI scans (e.g., due to metallic implants) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

PROCEDUREDynamic Contrast-Enhanced Magnetic Resonance Imaging

Undergo DCE-MRI

OTHERQuestionnaire Administration

Ancillary studies


Locations(1)

M D Anderson Cancer Center

Houston, Texas, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT03145077


Related Trials