Obesity, Metabolic Dysregulation and the Airway Epithelium in Asthmatics

This study is investigating how obesity and metabolic problems (like high blood sugar or insulin resistance) affect the cells lining the airways in people with asthma, compared to people without asthma. **You may be eligible if...** - You are between 18 and 65 years old - You have a doctor's diagnosis of asthma OR you are a healthy non-asthmatic participant - You have smoked fewer than 10 packs per year total, and have not smoked in the past year - You may participate even if you take blood pressure medication or manage diabetes through diet and exercise only **You may NOT be eligible if...** - You currently smoke or have significant smoking history (more than 10 pack-years) - You have a serious medical condition beyond asthma - You are pregnant - You use insulin or diabetes medications beyond diet and exercise control Talk to your doctor to see if this trial is right for you.