RecruitingNot ApplicableNCT03252795

Uterus Transplantation From a Multi-organ Donor

Uterus Transplantation From a Multi-organ Donor: A Prospective Trial


Sponsor

University Hospital, Ghent

Enrollment

20 participants

Start Date

Nov 3, 2016

Study Type

INTERVENTIONAL

Conditions

Summary

Uterus transplantation: screening, in vitro fertilization \[IVF\] treatment to be able to freeze embryos, uterus transplantation, pregnancy and afterwards removal of the uterus.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 38 Years

Inclusion Criteria9

  • Female with Maier-Rokitansky-Kuster-Hauser syndrome
  • Mucosal neovagina of at least 7 cm
  • In a stable relationship for at least 1 year
  • Child wish
  • Good renal function (and presence of both kidneys)
  • Psychologically stable and compliant
  • At least 8 frozen embryos after IVF/intracytoplasmic sperm injection \[ICSI\]
  • Living in Belgium and a good health insurance
  • Willing and able to provide informed consent

Exclusion Criteria4

  • Major pelvic surgery
  • Major chronic illnesses
  • Other risk factors or malignancies
  • BMI > 30

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Interventions

PROCEDUREuterus transplantation

transplantation of a uterus from a deceased donor


Locations(1)

Ghent University Hospital - Women's Clinic

Ghent, Belgium

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NCT03252795


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