RecruitingNCT03303833
The GEOLynch Cohort Study
The GEOLynch Cohort Study: Genetic, Environmental and Other Factors That Influence Tumour Risk Among Persons With Lynch Syndrome
Sponsor
Wageningen University
Enrollment
1,000 participants
Start Date
Jul 1, 2006
Study Type
OBSERVATIONAL
Conditions
Summary
The GEOLynch cohort study has been established to investigate the influence of genetic, environmental and other factors on tumour risk in persons with Lynch syndrome.
Eligibility
Min Age: 18 YearsMax Age: 80 Years
Inclusion Criteria2
- Persons with a known mutation in a gene that causes Lynch syndrome, i.e. with an inherited monoallelic pathogenic germline mutation in either the MLH1, MSH2, MSH6, PMS2 or EPCAM gene.
- Aged between 18 and 80 years at inclusion.
Exclusion Criteria5
- Additional carrier of another hereditary colon cancer predisposition syndrome (e.g. FAP)
- (Chronic) Inflammatory bowel disease
- Non-Dutch speaking
- Dementia or another mental condition that makes it impossible to fill out questionnaires
- Terminally ill persons
Interventions
OTHERNo intervention, observational study.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT03303833
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