Berlin-Brandenburg Pregnancy Cohort
Characterization of Immune Cell-trophoblast-interaction in Pregnancy Disorders
Charite University, Berlin, Germany
1,580 participants
Sep 26, 2017
OBSERVATIONAL
Conditions
Summary
This study will investigate the interplay of different immune cells and placental cells as well as their potential for the development of pregnancy complications. In particular, the translation of the uteroplacental syndrome into a maternal syndrome, considered in the multifactorial pregnancy disorder preeclampsia, will be investigated. Immune cell subtypes are causally involved in the formation and translation of preeclampsia by inducing an endothelial dysfunction which leads to cardiovascular damage.
Eligibility
Inclusion Criteria2
- healthy pregnant women after giving informed consent
- pregnant with diagnosis of preeclampsia, gestational hypertension or gestational diabetes
Exclusion Criteria3
- infections
- alcohol and drug abuse
- manifest and chronic diseases
Locations(1)
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NCT03313024