RecruitingNot ApplicableNCT03385720

Submandibular Gland Preservation in Neck Dissection

Submandibular Gland Preservation During Neck Dissection for Oral Squamous Cell Carcinoma

Sponsor

Guang-Yan Yu

Enrollment

200 participants

Start Date

Dec 5, 2017

Study Type

INTERVENTIONAL

Conditions

Oral Cancer Neck Dislocation

Summary

Trial design: a randomized controlled trial. Eligibility criteria for participants: patients with primary early stage oral squamous cell carcinoma. Exclusion criteria: cancer of the floor of the mouth. Interventions: submandibular gland is preserved during neck dissection for patients of the experimental group; submandibular gland is removed during neck dissection for patients of the control group. Primary Parameters: survival rate, mortality rate

Eligibility

Max Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This trial is studying whether the salivary gland under the jaw (the submandibular gland) can safely be preserved during neck lymph node removal surgery in patients with early-stage mouth cancer, without affecting cancer control outcomes. **You may be eligible if...** - You have been diagnosed with primary squamous cell carcinoma (a type of cancer) of the mouth at an early stage (T1N0 or T2N0 — meaning the tumor is small and has not spread to lymph nodes) **You may NOT be eligible if...** - Your cancer started in the floor of the mouth (the area underneath the tongue), as this location is close to the submandibular gland and preserving it may not be safe in that situation Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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