Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia

This trial is testing whether high-dose intravenous vitamin C given alongside chemotherapy can improve outcomes for patients with lymphoma (blood cancer) or certain types of leukemia that have come back or stopped responding to treatment. **You may be eligible if...** - You are 18 years or older - You have a diagnosed lymphoma or a specific type of leukemia (CCUS or chronic myelomonocytic leukemia) that has relapsed or is not responding to treatment - You have not received certain prior chemotherapy regimens (varies by treatment arm) - You are in generally good health and your organs are functioning adequately - You are not pregnant and are willing to use contraception if applicable **You may NOT be eligible if...** - Your cancer has spread to the brain or spinal fluid - You have a G6PD enzyme deficiency (a genetic condition that can cause a reaction to high-dose vitamin C) - You are currently receiving other investigational treatments - You have serious kidney problems or are on dialysis - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.