RecruitingNCT03455868

Bone Health After Bariatric Surgery in Patients With Type 2 Diabetes


Sponsor

CHU de Quebec-Universite Laval

Enrollment

100 participants

Start Date

Mar 15, 2018

Study Type

OBSERVATIONAL

Conditions

Summary

Background: Bone fragility is a complication of type 2 diabetes. Diabetes treatments may ameliorate or deteriorate bone fragility in this population. Bariatric surgery is gaining in popularity in people with type 2 diabetes and may impact bone health. Objectives: To evaluate the impact of the most popular bariatric procedure worldwide (sleeve gastrectomy (SG)) on vBMD by QCT in patients with type 2 diabetes; Secondary aims: (1) to identify the determinants of vBMD after bariatric surgery in patients with type 2 diabetes; (2) to compare vBMD and its potential determinants after bariatric surgery with obese controls without diabetes as well as with controls without obesity and normoglycemia.


Eligibility

Min Age: 18 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at how bariatric (weight-loss) surgery affects bone health in people with type 2 diabetes, to understand whether the surgery causes bone loss and what factors may increase that risk. **You may be eligible if...** - You are between 18 and 60 years old - You have a BMI of 35 or higher and are awaiting bariatric surgery - You have been diagnosed with type 2 diabetes, OR you do not have diabetes - A healthy-weight control group (BMI 25–29.9, no diabetes) is also enrolling **You may NOT be eligible if...** - You have type 1 diabetes - You have a condition affecting bone health (e.g., uncontrolled thyroid disease, metabolic bone disease) or take medications that affect bones (e.g., steroids, anti-seizure drugs, osteoporosis medications) - Your BMI is above 60 - You are pregnant, planning to become pregnant, or not using contraception during the study - You have had previous stomach or intestinal surgery, including prior bariatric surgery - You have active cancer or another serious chronic illness - You have a metal implant that would interfere with the imaging tests Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

PROCEDUREBariatric surgery

Sleeve gastrectomy


Locations(3)

The Research Institute of the McGill University Health Centre

Montreal, Quebec, Canada

Centre de recherche du CHU de Québec - Université Laval

Québec, Quebec, Canada

Centre de recherche de l'IUCPQ

Québec, Quebec, Canada

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT03455868


Related Trials