RecruitingNCT03483337

New MRI Biomarkers in Head and Neck Cancers

Quantitative Imaging Tools to Derive DW-MRI Oncological Biomarkers


Sponsor

Memorial Sloan Kettering Cancer Center

Enrollment

200 participants

Start Date

Mar 16, 2018

Study Type

OBSERVATIONAL

Conditions

Summary

Magnetic resonance imaging (MRI) is a diagnostic technique that takes pictures of organs of the body. It uses magnetic fields and radio waves that cannot be felt. This makes specific organs, blood vessels, or tumors easier to see. Diffusion MRI lets us measure the motion of water in the tumor. The purpose of this study is to see if new MRI methods can give us more information about the tumor.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is evaluating new MRI techniques to better detect and monitor head and neck cancers — including thyroid cancer — that have come back or spread to the neck, to determine if these advanced scans provide more useful information than standard imaging. **You may be eligible if...** - You are 18 or older - You fall into one of two groups: - You have a suspicious lesion in the head/neck area that may be a returning or spreading cancer - You have a confirmed diagnosis of recurrent, metastatic, or active head and neck cancer (including certain thyroid cancers) and are planning treatment at MSK (Memorial Sloan Kettering) **You may NOT be eligible if...** - You would need sedation or anesthesia for the MRI - You have claustrophobia - You are receiving cancer treatment at a different institution - You have a known allergy to gadolinium-based MRI contrast dye - You have a pacemaker, aneurysm clips, or other metal implants that are not MRI-safe - You are pregnant - You are unable to cooperate with the MRI procedure Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERMRI examinations

Patients will be imaged on a 1.5 T or 3 T MR scanner either from GE or Philips. Patients will receive a test-retest scan in on session prior to start of treatment. Patients who will be receiving radiation therapy treatment at main campus, will also be imaged weekly during their course of treatment.

OTHERMRI examinations

Patients will be imaged on a 1.5 T or 3T MR scanner within one week prior to treatment initiation and at two months and four months after treatment completion (+/- 1 week).


Locations(1)

Memorial Sloan Kettering Cancer Center

New York, New York, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT03483337


Related Trials