RecruitingNCT03592563

CUHK Brain Health Longitudinal Study

Sponsor

Chinese University of Hong Kong

Enrollment

5,000 participants

Start Date

Jul 1, 2019

Study Type

OBSERVATIONAL

Conditions

Dementia Brain Diseases Health Knowledge, Attitudes, Practice Stroke, Ischemic Stroke Alzheimer Disease Stroke, Acute Healthy Aging Stroke Syndrome Brain Ischemia Health Attitude Health Personnel Attitude

Summary

The goal of this study is to develop a large longitudinal cohort of individuals diagnosed with or at high risk for brain diseases (both neurological and psychiatric in nature), in order to identify risk factors that contribute to neurological and psychiatric diseases over time. The investigators seek to capture relevant information from medical records, electronically administered questionnaires and follow up phone-based interviews. The investigators expect to eventually have sufficient power from our dataset to examine risk factors for a variety of brain disorders, both individually and in aggregate. Our ultimate goal is to offer scientifically validated ways to preserve and promote brain health by working with our patients' needs and tracking their progress over time.

Eligibility

Min Age: 18 Years

Inclusion Criteria9

Adult ≥ 18 years of age
Fulfilling criteria for membership in one of these three groups:
Red group: established diagnosis of one or more neurological and/or psychiatric conditions
Yellow group: high-risk to develop one or more neurological and/or psychiatric conditions
family history (first degree relative) one or more neurological and/or psychiatric conditions
examination, imaging or laboratory findings consistent with pre-symptomatic stages of one or more neurological and/or psychiatric disorders
Green group: not meeting criteria for Red or Yellow groups, but interested in longitudinal research on maintenance and/or improvement of brain health
Subject provides informed consent by signing and dating the written informed consent form
Subject is willing to answer health questionnaires and be followed longitudinally

Exclusion Criteria1

None

Interventions

BEHAVIORALNeuro-QoL questionnaire

Follow-up over time will continue (either in-person or over the phone) using the same questionnaires (depending on which group they are belongs to) at approximately 6-month intervals. During each follow-up, participants will be screened for any new signs, symptoms and diagnoses of neurological and/or psychiatric disorders, in order to correlate these outcomes with risk factors captured using the procedures described above.