New CSF Biomarkers for Alzheimer's Disease

This study is collecting samples of cerebrospinal fluid (the fluid around the brain and spinal cord) from people undergoing a lumbar puncture (spinal tap) as part of their routine memory loss or dementia evaluation, to search for new biological markers that could help diagnose Alzheimer's disease earlier and more accurately. **You may be eligible if...** - You are already undergoing a lumbar puncture (spinal tap) as part of your routine care for a dementia or memory disorder evaluation - You are willing to give consent to have your samples included in the study **You may NOT be eligible if...** - You do not give consent for your samples to be used in the study - Your lumbar puncture is being done for a reason unrelated to memory or dementia assessment Talk to your doctor to see if this trial is right for you.