Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy
Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy/Adenoidectomy: Randomized Control Trial
Children's Healthcare of Atlanta
50 participants
Jul 31, 2018
INTERVENTIONAL
Conditions
Summary
The purpose of this pilot study: 1) to examine the use of gabapentin in reducing pain in the first 48 hours postoperatively including the total amount of narcotics mg/kg given 2) to record the time to first analgesic postoperatively and 3) to compare Wong Baker and the 0-10 numeric pain distress scale scores at 12, 24 and 48 hours postoperatively. We hypothesize one 15mg/kg (up to 600mg) dose of gabapentin will decrease mean narcotic amounts in mg/kg compared to participants who do not receive preoperative gabapentin and will demonstrate a decreased mean time to first analgesic as well as to lower mean pain scores for each age group at 12, 24 and 48 hours.
Eligibility
Inclusion Criteria4
- participants age 3-18 years
- ASA class 1 or 2
- elective Tonsillectomy/Adenoidectomy
- outpatient setting.
Exclusion Criteria4
- BMI \>40kg/m2
- history of renal insufficiency, chronic pain
- allergy to gabapentin
- history of developmental delay
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Interventions
This double blinded randomized control trial will enroll 50 children age 3-18 years, undergoing T/As. Patients will be receiving either one gabapentin dose (15mg/kg up to 600mg) or placebo preoperatively. Both control and test group will receive the standard narcotic regimen intraoperatively.
Locations(1)
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NCT03625011