NSAIDs Stent Study

This study is evaluating whether using non-steroidal anti-inflammatory drugs (NSAIDs) — common pain relievers like ibuprofen — after ureteral stent placement following kidney stone removal can reduce stent-related discomfort and pain. Ureteral stents are small tubes placed inside the ureter (the tube connecting the kidney to the bladder) after certain procedures to keep the urinary tract open and draining. Stent-related symptoms, including pain, urgency, and discomfort during urination, are extremely common and significantly affect quality of life. This trial will determine whether a short course of NSAIDs can effectively manage these symptoms. You may be eligible if: - You are over 18 years old - You have kidney stones and are planning to undergo ureteroscopic stone removal with ureteral stent placement You may NOT be eligible if: - You are having a procedure on both sides (bilateral) - You use NSAIDs regularly (more than 15 days in the past month, except aspirin 81 mg daily) - You take steroid or prescription anti-inflammatory medications - You have gastrointestinal ulcers, active urinary tract infection, or a pre-existing stent - You are pregnant or breastfeeding - You have kidney or liver problems Talk to your doctor to see if this trial is right for you.