Kidney Stone Clinical Trials

59 recruitingLast updated: July 25, 2026

There are 59 actively recruiting kidney stone clinical trials across 16 countries. Studies span Not Applicable, Early Phase 1, Phase 3, Phase 4, Phase 2. Top locations include Chicago, Illinois, United States, Birmingham, Alabama, United States, Kansas City, Kansas, United States. Updated daily from ClinicalTrials.gov.


Kidney Stone Trials at a Glance

59 actively recruiting trials for kidney stone are listed on ClinicalTrialsFinder across 6 cities in 16 countries. The largest study group is Not Applicable with 43 trials, with the heaviest enrollment activity in Chicago, Birmingham, and Kansas City. Lead sponsors running kidney stone studies include University of Alabama at Birmingham, University of Chicago, and The First Affiliated Hospital of Guangzhou Medical University.

Browse kidney stone trials by phase

Treatments under study

About Kidney Stone Clinical Trials

Looking for clinical trials for Kidney Stone? There are currently 34 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Kidney Stone trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Kidney Stone clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 59 trials

Recruiting
Not Applicable

Trial of Ureteroscopy vs Steerable Continuous Flow Aspiration Technology

Renal StonesKidney StonesUrolithiasis+1 more
Calyxo, Inc.150 enrolled5 locationsNCT07101809
Recruiting
Not Applicable

Effects of Virtual Reality Education on Anxiety and Learning in Patients Undergoing Urolithiasis Surgery

Kidney StoneUrolithiasisUreter Stones
Wei-Lin, Huang90 enrolled1 locationNCT07620873
Recruiting

Stone and Laser Therapies Post-Market Study (SALT)

Benign Prostate Hypertrophy(BPH)Ureteral Stones, Kidney StonesCalculi, Urinary+2 more
Boston Scientific Corporation238 enrolled5 locationsNCT06982235
Recruiting

Kidney Stone Inflammation

Kidney StoneStone, Kidney
University of Chicago40 enrolled1 locationNCT06436235
Recruiting
Not Applicable

Comparison of Vacuum-Assisted and Conventional Ureteral Access Sheath in Retrograde Intrarenal Surgery

Kidney StonesKidney Calculi
Namik Kemal University150 enrolled1 locationNCT06684756
Recruiting
Not Applicable

Thulium Fiber Laser (TFL) vs Thulio Pulsed Thulium:YAG (p-Tm:YAG)

Kidney StonesNephrolithiasis
University of California, San Diego50 enrolled1 locationNCT06721975
Recruiting
Not Applicable

Modified Mini-PCNL Versus Standard PCNL for Complex Kidney Stones

Kidney StonesComplex Renal Calculi
The First Affiliated Hospital of Guangzhou Medical University1,380 enrolled1 locationNCT07697677
Recruiting
Phase 3

Trial to Assess the Efficacy of EMPAgliflozin and Personalized Dietary Counseling for Kidney STONE Prevention

Dietary ExposureNephrolithiasisKidney Stone
Insel Gruppe AG, University Hospital Bern400 enrolled21 locationsNCT06653738
Recruiting
Not Applicable

Randomized Controlled Trial of Miniaturized Percutaneous Nephrolithotomy With Vacuum-Assisted Access Sheaths Versus Conventional Sheaths for Treatment of Nephrolithiasis

Kidney Stone
The Cleveland Clinic90 enrolled1 locationNCT05993546
Recruiting
Not Applicable

PMCF Investigation of MODULITH® SLX-F2 With StorM-Track in Patients With Kidney Stones

Kidney StonesUrolithiasis
Storz Medical AG126 enrolled1 locationNCT07272720
Recruiting
Not Applicable

Ureteral Access Sheaths in Endoscopic Kidney Stone Surgery

Kidney Stones
Hitit University70 enrolled1 locationNCT07568990
Recruiting
Phase 4

Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary Stones

Calcium Phosphate Kidney Stones
University of Texas Southwestern Medical Center25 enrolled1 locationNCT06003348
Recruiting
Not Applicable

Endogenous Oxalate Synthesis in Idiopathic Calcium Oxalate Kidney Stone Disease

HealthyHealthy VolunteerKidney Stones+6 more
University of Alabama at Birmingham80 enrolled2 locationsNCT06989320
Recruiting
Not Applicable

O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease

NephrolithiasisKidney StoneUrolithiasis+5 more
University of Alabama at Birmingham40 enrolled2 locationsNCT06330246
Recruiting
Not Applicable

Gut Oxalate Absorption in Calcium Oxalate Stone Disease

HealthyNephrolithiasisKidney Stone+6 more
University of Alabama at Birmingham80 enrolled2 locationsNCT06331546
Recruiting
Not Applicable

Evaluation of Eye Gaze Sharing in the Operating Room

Kidney Stones
Vanderbilt University Medical Center110 enrolled1 locationNCT07173309
Recruiting
Not Applicable

Oxalate-Driven Host Responses in Kidney Stone Disease

Kidney Stones
University of Alabama at Birmingham88 enrolled1 locationNCT05417568
Recruiting
Not Applicable

A Novel Ureteric Stent in Kidney Stone Patients and Oncology Patients Compared to a Conventional JJ Stent

OncologyKidney StoneCatheter Blockage
University of Southampton50 enrolled2 locationsNCT06815120
Recruiting
Not Applicable

Surgical Outcomes and Costs in Using the Shenzhen HugeMed 6.3 French Flexible Ureteroscope

Kidney Stones
University of Kansas Medical Center75 enrolled1 locationNCT07296835
Recruiting
Not Applicable

Evaluation of the LithoVue Elite Ureteroscope With Intra-Renal Pressure Monitoring Technology: Examination of Surgeon Behavior and Post-operative Outcomes

NephrolithiasisKidney Stone
University of Kansas Medical Center80 enrolled1 locationNCT06576661