HoYAG vs TFL in miniPCNL With ClearPetra
Holmium:YAG Laser With MOSES Technology vs Thulium Fiber Laser in Supine Mini-percutaneous Nephrolithotomy With Vacuum-assisted Renal Access Sheath: A Prospective, Randomized Clinical Trial
University of Kansas Medical Center
150 participants
Aug 22, 2025
INTERVENTIONAL
Conditions
Summary
Mini percutaneous nephrolithotripsy is the treatment of choice for kidney stones over 2cm. This procedure commonly uses laser energy for breaking the stones, and among possible laser platforms, Hoyag and thulium fiber laser are FDA approved. Recently, this procedure has also included the use of vacuum assisted renal access sheaths, which allows suction to be employed together with the breaking of stones. This study intends to compare outcomes when using either laser platforms with suction sheaths in participants undergoing mini percutaneous nephrolithotripsy for the treatment of kidney stones.
Eligibility
Inclusion Criteria3
- Males or females over 18 years of age
- Patients with kidney stones, with stone burden larger than 15 mm.
- Patients undergoing new percutaneous access with primary, supine, unilateral mini-PCNL.
Exclusion Criteria9
- Simultaneous use of more than 1 laser platform or other form of fragmentation (e.g., ultrasonic).
- Patients undergoing simultaneous treatment of contralateral kidney stones during the same procedure.
- Patients undergoing simultaneous treatment of ureteral stones during the same procedure.
- Pregnant patients.
- Presence of genitourinary anatomical abnormalities.
- Uncorrected coagulopathy.
- External urinary catheters.
- Immunosuppressed patients.
- Non-elective procedures.
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Interventions
Patients will be randomly assigned (1:1) to HoYAG laser or TFL laser group for miniPCNL surgery according to standard of care.
Patients will be randomly assigned (1:1) to HoYAG or TFL laser group for MiniPCNL surgery according to standard of care.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07087977